Enantioselective Reduction of Aromatic and Aliphatic Ketones Catalyzed by Ruthenium Complexes Attached to β-Cyclodextrin

2004 ◽  
Vol 116 (48) ◽  
pp. 6899-6902 ◽  
Author(s):  
Alain Schlatter ◽  
Mrinal K. Kundu ◽  
Wolf-D. Woggon
Keyword(s):  
Ruthenium Complexes ◽  
Enantioselective Reduction ◽  
Aliphatic Ketones

Reaction Engineering of Biocatalytic Enantioselective Reduction: A Case Study for Aliphatic Ketones

2013 ◽  
Vol 17 (8) ◽  
pp. 1027-1035 ◽  
Author(s):  
Susanne Leuchs ◽  
Joana Lima-Ramos ◽  
Lasse Greiner ◽  
Naweed Al-Haque ◽  
Pär Tufvesson ◽  
...  
Keyword(s):  
Reaction Engineering ◽  
Enantioselective Reduction ◽  
Aliphatic Ketones

Enantioselective Reduction of Aliphatic Ketones Using Oxazaborolidine Catalyst Generated In Situ from Chiral Lactam Alcohol and Phenoxyborane

2009 ◽  
Vol 38 (7) ◽  
pp. 722-723 ◽  
Author(s):  
Yasuhiro Kawanami ◽  
Yudai Mikami ◽  
Katsuhiro Hoshino ◽  
Mikiko Suzue ◽  
Izumi Kajihara
Keyword(s):  
Enantioselective Reduction ◽  
Aliphatic Ketones

scholarly journals Enantioselective reduction of prochiral ketones promoted by amino amide ruthenium complexes: A DFT study

2021 ◽  
Vol 939 ◽  
pp. 121765
Author(s):  
Y. Meftah ◽  
Y. Boumedjane ◽  
P. Fleurat-Lessard ◽  
F. Delbecq ◽  
C. Michel
Keyword(s):  
Ruthenium Complexes ◽  
Dft Study ◽  
Enantioselective Reduction ◽  
Amino Amide ◽  
Prochiral Ketones

scholarly journals Practical Enantioselective Reduction of Ketones Using Oxazaborolidine Catalysts Generated In Situ from Chiral Lactam Alcohols

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2408 ◽  
Author(s):  
Yasuhiro Kawanami ◽  
Ryo Yanagita
Keyword(s):  
Practical Method ◽  
Enantioselective Reduction ◽  
Trifluoromethyl Ketones ◽  
Aliphatic Ketones ◽  
Borane Reduction ◽  
Absolute Stereochemistry ◽  
Reduction Of Ketones

Oxazaborolidine catalyst (CBS catalyst) has been extensively used for catalytic borane reduction with a predictable absolute stereochemistry and high enantioselectivity. However, the use of isolated CBS catalyst sometimes has the drawback of low reproducibility due to the aging of the CBS catalyst during storage. Therefore, we investigated a more reliable and practical method for the reduction of a variety of ketones including challenging substrates, primary aliphatic ketones, α,β-enones, and trifluoromethyl ketones. This review surveys the developments in borane reduction using oxazaborolidine catalysts generated in situ from chiral lactam alcohols and borane.

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