Tissue plasminogen activator in peripheral arterial thrombolysis

1990 ◽  
Vol 77 (8) ◽  
pp. 954-955
Author(s):  
K. Dawson ◽  
G. Stansby ◽  
R. Novell ◽  
D. Hehir ◽  
D. C. Berridge ◽  
...  
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Tissue Plasminogen ◽  
Peripheral Arterial ◽  
Arterial Thrombolysis

Distant haemorrhagic effects in intra-arterial Tissue Plasminogen Activator The effect of a bolus dose

1994 ◽  
Vol 80 (2) ◽  
pp. 66-70
Author(s):  
N P J Cripps ◽  
A S Ward
Keyword(s):  
Continuous Infusion ◽  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Bolus Dose ◽  
Entry Site ◽  
Arterial Tissue ◽  
Tissue Plasminogen ◽  
Peripheral Arterial ◽  
Haemorrhage Rate ◽  
Arterial Thrombolysis

AbstractDetails are reported of four patients who developed serious distant haemorrhagic complications while undergoing peripheral arterial thrombolysis with intra-arterial tissue plasminogen activator (t-PA). The thrombolytic regime comprised a 20 mg bolus of t-PA followed by a continuous infusion of 1 mg/hr. Four additional cases of haemorrhage at the catheter entry site were also encountered in a group of 23 patients exposed to the bolus-infusion t-PA regimen. The high haemorrhage rate (31 % ) is a significant disadvantage of this thrombolytic protocol.

Tissue plasminogen activator in peripheral arterial thrombolysis

1990 ◽  
Vol 77 (2) ◽  
pp. 179-182 ◽  
Author(s):  
D. C. Berridge ◽  
R. H. S. Gregson ◽  
G. S. Makin ◽  
B. R. Hopkinson
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Tissue Plasminogen ◽  
Peripheral Arterial ◽  
Arterial Thrombolysis
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