Virus filtration of high-concentration monoclonal antibody solutions

2009 ◽  
Vol 25 (2) ◽  
pp. 483-491 ◽  
Author(s):  
Bruno F. Marques ◽  
David J. Roush ◽  
Kent E. Göklen
Keyword(s):  
Monoclonal Antibody ◽  
High Concentration ◽  
Virus Filtration

scholarly journals P09-16. A primary R5 isolate undergoes different escape pathway during in vitro selection with low or high concentration of an anti-V3 monoclonal antibody

Retrovirology ◽  
2009 ◽  
Vol 6 (S3) ◽  
Author(s):  
C Narahara ◽  
M Hatada ◽  
H Shigeyoshi ◽  
K Yoshimura ◽  
S Matsushita
Keyword(s):  
Monoclonal Antibody ◽  
In Vitro Selection ◽  
High Concentration

scholarly journals High concentration tangential flow ultrafiltration of stable monoclonal antibody solutions with low viscosities

2016 ◽  
Vol 508 ◽  
pp. 113-126 ◽  
Author(s):  
Jessica J. Hung ◽  
Ameya U. Borwankar ◽  
Barton J. Dear ◽  
Thomas M. Truskett ◽  
Keith P. Johnston
Keyword(s):  
Monoclonal Antibody ◽  
High Concentration ◽  
Tangential Flow

Lyophilization Cycle Development for a High-Concentration Monoclonal Antibody Formulation Lacking a Crystalline Bulking Agent

2007 ◽  
Vol 96 (6) ◽  
pp. 1598-1608 ◽  
Author(s):  
James D. Colandene ◽  
Linda M. Maldonado ◽  
Alma T. Creagh ◽  
John S. Vrettos ◽  
Kenneth G. Goad ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Bulking Agent ◽  
High Concentration

A Formulation Development Approach to Identify and Select Stable Ultra–High-Concentration Monoclonal Antibody Formulations With Reduced Viscosities

2017 ◽  
Vol 106 (11) ◽  
pp. 3230-3241 ◽  
Author(s):  
Neal Whitaker ◽  
Jian Xiong ◽  
Samantha E. Pace ◽  
Vineet Kumar ◽  
C. Russell Middaugh ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Formulation Development ◽  
High Concentration ◽  
Development Approach

Adapting virus filtration to enable intensified and continuous monoclonal antibody processing

2020 ◽  
Author(s):  
David M. Bohonak ◽  
Ushma Mehta ◽  
Eric R. Weiss ◽  
Greg Voyta
Keyword(s):  
Monoclonal Antibody ◽  
Virus Filtration

Predicting High-Concentration Interactions of Monoclonal Antibody Solutions: Comparison of Theoretical Approaches for Strongly Attractive Versus Repulsive Conditions

2019 ◽  
Vol 123 (27) ◽  
pp. 5709-5720 ◽  
Author(s):  
Cesar Calero-Rubio ◽  
Atul Saluja ◽  
Erinc Sahin ◽  
Christopher J. Roberts
Keyword(s):  
Monoclonal Antibody ◽  
High Concentration ◽  
Theoretical Approaches

Characterization of the photodegradation of a human IgG1 monoclonal antibody formulated as a high-concentration liquid dosage form

2009 ◽  
Vol 98 (9) ◽  
pp. 3117-3130 ◽  
Author(s):  
Pei Qi ◽  
David B. Volkin ◽  
Hui Zhao ◽  
Michael L. Nedved ◽  
Robert Hughes ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Dosage Form ◽  
High Concentration ◽  
Igg1 Monoclonal Antibody ◽  
Human Igg1 ◽  
Liquid Dosage Form ◽  
Human Igg1 Monoclonal Antibody

Characterizing protein–protein-interaction in high-concentration monoclonal antibody systems with the quartz crystal microbalance

2017 ◽  
Vol 19 (48) ◽  
pp. 32698-32707 ◽  
Author(s):  
Josef Hartl ◽  
Astrid Peschel ◽  
Diethelm Johannsmann ◽  
Patrick Garidel
Keyword(s):  
Monoclonal Antibody ◽  
Quartz Crystal Microbalance ◽  
Protein Interaction ◽  
Quartz Crystal ◽  
Therapeutic Antibodies ◽  
High Concentration ◽  
Concentrated Solutions ◽  
Protein Protein Interaction

Making use of a quartz crystal microbalance, concentrated solutions of therapeutic antibodies were studied with respect to their behavior under shear excitation with frequencies in the MHz range.

Sign in / Sign up

Export Citation Format

Share Document