Minimally invasive insertion of an equine stented pulmonary valve with a built-in sinus portion in a sheep model

To assess the clinical course of a sheep stifle joint model for osteochondral (OC) defects, medial femoral condyles (MFC) were exposed without patella luxation using medial parapatellar skin (3–4 cm) and deep incisions (2–3 cm). Two defects (7 mm diameter; 10 mm depth; OC punch) were left empty or refilled with osteochondral autologous transplantation cylinders (OATS) and explanted after six weeks. Incision-to-suture time, anesthesia time, and postoperative wound or impairment scores were compared to those in sham-operated animals. Implant performance was assessed by X-ray, micro-computed tomography, histology, and immunohistology (collagens 1, 2; aggrecan). There were no surgery-related infections or patellar luxations. Operation, anesthesia, and time to complete stand were short (0.5, 1.4, and 1.5 h, respectively). The wound trauma score was low (0.4 of maximally 4; day 7). Empty-defect and OATS animals reached an impairment score of 0 significantly later than sham animals (7.4 and 4.0 days, respectively, versus 1.5 days). Empty defects showed incomplete healing and dedifferentiation/heterotopic differentiation; OATS-filled defects displayed advanced bone healing with remaining cartilage gaps and orthotopic expression of bone and cartilage markers. Minimally-invasive, medial parapatellar surgery of OC defects on the sheep MFC allows rapid and low-trauma recovery and appears well-suited for implant testing.

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First Results of a Stented Completely Tissue-Engineered Pulmonary Valve Replacement for Transcatheter Implantation in an Intermediate-Term Sheep Model

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0033-1354438 ◽

2013 ◽

Vol 61 (S 02) ◽

Author(s):

B Schmitt ◽

F Berger

Keyword(s):

Valve Replacement ◽

Pulmonary Valve ◽

Pulmonary Valve Replacement ◽

Sheep Model ◽

First Results ◽

Transcatheter Implantation

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Implantation of a modified stented bovine pulmonary valve in a beating heart sheep model

Journal of Cardiac Surgery ◽

10.1111/jocs.13185 ◽

2017 ◽

Vol 32 (8) ◽

pp. 508-513 ◽

Cited By ~ 1

Author(s):

Yongshan Zhang ◽

Fei Teng ◽

Juan Xiao ◽

Weiguo Bao ◽

Qingling Zhou ◽

...

Keyword(s):

Pulmonary Valve ◽

Beating Heart ◽

Sheep Model

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Commentary: Minimally invasive pulmonary valve replacement and the adoption curve for novel techniques

JTCVS Techniques ◽

10.1016/j.xjtc.2020.12.030 ◽

2020 ◽

Author(s):

Joseph R. Nellis ◽

Joseph W. Turek ◽

Nicholas D. Andersen

Keyword(s):

Minimally Invasive ◽

Valve Replacement ◽

Pulmonary Valve ◽

Pulmonary Valve Replacement

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Considerations in Dysphagia Management Following Esophagectomy

Perspectives of the ASHA Special Interest Groups ◽

10.1044/persp1.sig13.169 ◽

2016 ◽

Vol 1 (13) ◽

pp. 169-176

Author(s):

Lisa M. Evangelista ◽

James L. Coyle

Keyword(s):

Esophageal Cancer ◽

Minimally Invasive ◽

Minimally Invasive Surgical Procedures ◽

Esophageal Resection ◽

Minimally Invasive Surgical ◽

Operative Complications ◽

Swallowing Difficulties ◽

Epidemiological Impact ◽

Invasive Techniques ◽

Management Of Dysphagia

Esophageal cancer is the sixth leading cause of death from cancer worldwide. Esophageal resection is the mainstay treatment for cancers of the esophagus. While curative, surgical resection may result in swallowing difficulties that require intervention from speech-language pathologists (SLPs). Minimally invasive surgical procedures for esophageal resection have aimed to reduce morbidity and mortality associated with more invasive techniques. Both intra-operative and post-operative complications, regardless of the surgical approach, can result in dysphagia. This article will review the epidemiological impact of esophageal cancers, operative complications resulting in dysphagia, and clinical assessment and management of dysphagia pertinent to esophageal resection.

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