Comparison of acute kidney injury classifications in patients undergoing transcatheter aortic valve implantation: Predictors and long-term outcomes

2015 ◽  
Vol 87 (3) ◽  
pp. 523-531 ◽  
Author(s):  
Edward Koifman ◽  
Amit Segev ◽  
Paul Fefer ◽  
Israel Barbash ◽  
Avi Sabbag ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Kidney Injury ◽  
Long Term Outcomes ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Forced diuresis with matched hydration during transcatheter aortic valve implantation for Reducing Acute Kidney Injury: a randomized, sham-controlled study (REDUCE-AKI)

2019 ◽  
Vol 40 (38) ◽  
pp. 3169-3178 ◽  
Author(s):  
Yaron Arbel ◽  
Eyal Ben-Assa ◽  
Daniela Puzhevsky ◽  
Batia Litmanowicz ◽  
Naama Galli ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Kidney Injury ◽  
Transcatheter Aortic Valve ◽  
Forced Diuresis ◽  
Aortic Valve Implantation ◽  
Valve Implantation ◽  
Long Term Mortality

Abstract Aims Acute kidney injury (AKI) is a common complication following transcatheter aortic valve implantation (TAVI) and is associated with increased risk for short- and long-term mortality. In patients undergoing percutaneous coronary intervention (PCI), forced diuresis with matched hydration has been shown to reduce the incidence of AKI by ∼50%. The aim of the present study was to evaluate whether forced diuresis with matched intravenous hydration reduces AKI in patients undergoing TAVI. Methods and results Reducing Acute Kidney Injury (REDUCE-AKI) was a single-centre, prospective, randomized, double-blind sham-controlled clinical trial, designed to examine the effect of an automated matched saline infusion with urine output for the prevention of AKI in patients undergoing TAVI. A total of 136 TAVI patients were randomized, 68 in each group. Mean age was 83.9 ± 5 years and 41.2% were males. There were no differences in baseline characteristics between the two groups. The rate of AKI was not statistically different between the groups (25% in the active group vs. 19.1% in the sham group, P = 0.408). There was a significant increase in long-term mortality in the active group (27.9% vs. 13. 2% HR 3.744, 95% CI 1.51–9.28; P = 0.004). The study was terminated prematurely by the Data Safety Monitoring Board for futility and a possible signal of harm. Conclusions Unlike in PCI, forced diuresis with matched hydration does not prevent AKI in patients undergoing TAVI, and might be associated with increased long-term mortality. Future studies should focus on understanding the mechanisms behind these findings. Clinicaltrials.gov registration NCT01866800, 30 April 2013.

scholarly journals Clinical impact of acute kidney injury on short- and long-term outcomes after transcatheter aortic valve implantation with the CoreValve prosthesis

2015 ◽  
Vol 66 (1) ◽  
pp. 46-49 ◽  
Author(s):  
Antonio J. Muñoz-García ◽  
Erika Muñoz-García ◽  
Manuel F. Jiménez-Navarro ◽  
Antonio J. Domínguez-Franco ◽  
Juan H. Alonso-Briales ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Aortic Valve ◽  
Kidney Injury ◽  
Clinical Impact ◽  
Long Term Outcomes ◽  
Transcatheter Aortic Valve ◽  
Short And Long Term ◽  
Aortic Valve Implantation ◽  
Valve Implantation

scholarly journals Acute kidney injury after transcatheter aortic valve implantation: Incidence, predictors and impact on mortality

2014 ◽  
Vol 107 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Yacine Elhmidi ◽  
Sabine Bleiziffer ◽  
Marcus-André Deutsch ◽  
Markus Krane ◽  
Domenico Mazzitelli ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Kidney Injury ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Long Term Outcomes of Patients Treated With Transcatheter Aortic Valve Implantation

2020 ◽  
Author(s):  
Nili Schamroth Pravda ◽  
Pablo Codner ◽  
Hana Vaknin Assa ◽  
Guy Witberg ◽  
Abid Assali ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Long Term Outcomes ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation
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