Chiral Brønsted Acid Catalyzed Enantioconvergent Propargylic Substitution Reaction of Racemic Secondary Propargylic Alcohols with Thiols

2020 ◽  
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pp. 5747-5757 ◽  
Author(s):  
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Jun Kikuchi ◽  
Azusa Kondoh ◽  
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Construction of a quaternary stereogenic center was accomplished through the enantioselective intramolecular allylic substitution reaction of bis-trichloroacetimidate catalyzed by a chiral phosphoramide derivative.


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