ChemInform Abstract: Potential Antitumor Agents. Part 44. Synthesis and Antitumor Activity of New Classes of Diacridines: Importance of Linker Chain Rigidity for DNA Binding Kinetics and Biological Activity.

Potential antitumor agents. 44. Synthesis and antitumor activity of new classes of diacridines: importance of linker chain rigidity for DNA binding kinetics and biological activity

10.1021/jm00149a005 ◽

1985 ◽

Vol 28 (11) ◽

pp. 1568-1574 ◽

Cited By ~ 75

Author(s):

William A. Denny ◽

Graham J. Atwell ◽

Bruce C. Baguley ◽

Laurence P. G. Wakelin

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Activity ◽

Antitumor Agents ◽

Binding Kinetics ◽

Chain Rigidity ◽

Linker Chain ◽

Potential antitumor agents. 39. Anilino ring geometry of amsacrine and derivatives: relationship to DNA binding and antitumor activity

10.1021/jm00365a014 ◽

1983 ◽

Vol 26 (11) ◽

pp. 1625-1630 ◽

Cited By ~ 24

Author(s):

William A. Denny ◽

Graham J. Atwell ◽

Bruce C. Baguley

Keyword(s):

Dna Binding ◽

Antitumor Activity ◽

Antitumor Agents ◽

Ring Geometry ◽

Potential antitumor agents. 45. Synthesis, DNA-binding interaction, and biological activity of triacridine derivatives

10.1021/jm00151a011 ◽

1986 ◽

Vol 29 (1) ◽

pp. 69-74 ◽

Cited By ~ 20

Author(s):

Graham J. Atwell ◽

Bruce C. Baguley ◽

Dorota Wilmanska ◽

William A. Denny

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Interaction ◽

ChemInform Abstract: POTENTIAL ANTITUMOR AGENTS. 39. ANILINO RING GEOMETRY OF AMSACRINE AND DERIVATIVES: RELATIONSHIP TO DNA BINDING AND ANTITUMOR ACTIVITY

Chemischer Informationsdienst ◽

10.1002/chin.198415226 ◽

1984 ◽

Vol 15 (15) ◽

Author(s):

W. A. DENNY ◽

G. J. ATWELL ◽

B. C. BAGULEY

Keyword(s):

Dna Binding ◽

Antitumor Activity ◽

Antitumor Agents ◽

Ring Geometry ◽

ChemInform Abstract: Potential Antitumor Agents. Part 53. Synthesis, DNA Binding Properties, and Biological Activity of Perimidines Designed as “Minimal” DNA-Intercalating Agents.

ChemInform ◽

10.1002/chin.198815233 ◽

1988 ◽

Vol 19 (15) ◽

Author(s):

J. M. HERBERT ◽

P. D. WOODGATE ◽

W. A. DENNY

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Properties ◽

Intercalating Agents ◽

Dna Binding Properties ◽

Potential antitumor agents. 53. Synthesis, DNA binding properties, and biological activity of perimidines designed as minimal DNA-intercalating agents

10.1021/jm00394a025 ◽

1987 ◽

Vol 30 (11) ◽

pp. 2081-2086 ◽

Cited By ~ 63

Author(s):

John M. Herbert ◽

Paul D. Woodgate ◽

William A. Denny

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Properties ◽

Intercalating Agents ◽

Dna Binding Properties ◽

Relationships between DNA-binding kinetics and biological activity for the 9-aminoacridine-4-carboxamide class of antitumor agents

10.1021/jm00388a019 ◽

1987 ◽

Vol 30 (5) ◽

pp. 855-861 ◽

Cited By ~ 79

Author(s):

Laurence P. G. Wakelin ◽

Graham J. Atwell ◽

Gordon W. Rewcastle ◽

William A. Denny

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Kinetics

ChemInform Abstract: Potential Antitumor Agents. Synthesis, DNA Binding Studies, and Biological Activity of 9-Aminoacridinyl Derivatives of Citrulline and Arginine.

ChemInform ◽

10.1002/chin.199101221 ◽

2010 ◽

Vol 22 (1) ◽

pp. no-no ◽

Cited By ~ 1

Author(s):

M. RAD-NIKNAM ◽

D. SHARPLES

Keyword(s):

Biological Activity ◽

Dna Binding ◽

Antitumor Agents ◽

Binding Studies ◽

Dna Binding Studies ◽

Derivatives Of ◽

Monophosphoric acid diesters of 7.beta.-hydroxycholesterol and of pyrimidine nucleosides as potential antitumor agents: synthesis and preliminary evaluation of antitumor activity

10.1021/jm00170a034 ◽

1990 ◽

Vol 33 (8) ◽

pp. 2264-2270 ◽

Cited By ~ 21

Author(s):

Yu Hua Ji ◽

Christiane Moog ◽

Gaby Schmitt ◽

Pierre Bischoff ◽

Bang Luu

Keyword(s):

Antitumor Activity ◽

Antitumor Agents ◽

Preliminary Evaluation ◽

Pyrimidine Nucleosides ◽

ChemInform Abstract: POTENTIAL ANTITUMOR AGENTS. PART 43. SYNTHESIS AND BIOLOGICAL ACTIVITY OF DIBASIC 9-AMINOACRIDINE-4-CARBOXAMIDES, A NEW CLASS OF ANTITUMOR AGENT

Chemischer Informationsdienst ◽

10.1002/chin.198512225 ◽

1985 ◽

Vol 16 (12) ◽

Author(s):

G. J. ATWELL ◽

B. F. CAIN ◽

B. C. BAGULEY ◽

G. J. FINLAY ◽

W. A. DENNY

Keyword(s):

Biological Activity ◽

Antitumor Agents ◽

Antitumor Agent ◽

New Class ◽