ChemInform Abstract: Discovery and Synthesis of Methyl 2,5-Dimethyl-4-(2-(phenylmethyl) benzoyl)-1H-pyrrole-3-carboxylate (FPL 64176) and Analogues: The First Examples of a New Class of Calcium Channel Activator.

Discovery and synthesis of methyl 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxylate (FPL 64176) and analogs: the first examples of a new class of calcium channel activator

Journal of Medicinal Chemistry ◽

10.1021/jm00071a004 ◽

1993 ◽

Vol 36 (19) ◽

pp. 2739-2744 ◽

Cited By ~ 31

Author(s):

Andrew J. G. Baxter ◽

John Dixon ◽

Francis Ince ◽

Carol N. Manners ◽

Simon J. Teague

Keyword(s):

Calcium Channel ◽

New Class ◽

The non-dihydropyridine L-type voltage-sensitive calcium channel activator FPL 64176 enhances K+-evoked efflux of [3H]norepinephrine from rat neocortical slices

Neuroscience Letters ◽

10.1016/0304-3940(93)90433-l ◽

1993 ◽

Vol 156 (1-2) ◽

pp. 35-38 ◽

Cited By ~ 9

Author(s):

T. Ginap ◽

D.J. Dooley ◽

T.J. Feuerstein

Keyword(s):

Calcium Channel ◽

Maitotoxin, A Presumed Calcium Channel Activator, Induces the Acrosome Reaction in Mussel Spermatozoa. (maitotoxin/acrosome reaction/calcium channel activator/calcium channel antagonist/mussel sperm)

Development Growth & Differentiation ◽

10.1111/j.1440-169x.1986.00443.x ◽

1986 ◽

Vol 28 (5) ◽

pp. 443-448 ◽

Cited By ~ 6

Author(s):

ICHIRO NISHIYAMA ◽

TAEI MATSUI ◽

TAKESHI YASUMOTO ◽

SHIGERU OSHIO ◽

MOTONORI HOSHI

Keyword(s):

Calcium Channel ◽

Calcium Channel Antagonist ◽

Acrosome Reaction ◽

Synthesis of [3H]FPL 64176, a potent calcium channel activator

Journal of Labelled Compounds and Radiopharmaceuticals ◽

10.1002/jlcr.2580340710 ◽

1994 ◽

Vol 34 (7) ◽

pp. 659-662

Author(s):

Christian Foged ◽

Peter Madsen

Keyword(s):

Calcium Channel ◽

Sensitivity of α-Adrenoceptor Agonists to the Calcium Channel Activator, Bay K 8644, in Canine Saphenous Vein

Pharmacology ◽

10.1159/000138320 ◽

1987 ◽

Vol 35 (5) ◽

pp. 272-278 ◽

Cited By ~ 1

Author(s):

Hanna Eskinder ◽

Garrett J. Gross

Keyword(s):

Calcium Channel ◽

Saphenous Vein ◽

Bay K 8644 ◽

Alpha Adrenoceptor ◽

Canine Saphenous Vein ◽

Alpha Adrenoceptor Agonists ◽

Adrenoceptor Agonists ◽

Effects of the Calcium Channel Activator BAY-K-8644 onin VitroSecretion of Calcitonin and Parathyroid Hormone*

Endocrinology ◽

10.1210/endo-118-2-545 ◽

1986 ◽

Vol 118 (2) ◽

pp. 545-549 ◽

Cited By ~ 31

Author(s):

CARY W. COOPER ◽

SUSAN A. BOROSKY ◽

PATRICK E. FARRELL ◽

ODD S. STEINSLAND

Keyword(s):

Parathyroid Hormone ◽

Calcium Channel ◽

Bay K 8644 ◽

Failure of the calcium channel activator, Bay K 8644, to increase the release of acetylcholine from nerve terminals in brain and diaphragm

British Journal of Pharmacology ◽

10.1111/j.1476-5381.1987.tb11239.x ◽

1987 ◽

Vol 91 (3) ◽

pp. 475-479 ◽

Cited By ~ 16

Author(s):

Vladimír Doležal ◽

Stanislav Tuček

Keyword(s):

Calcium Channel ◽

Bay K 8644 ◽

Nerve Terminals ◽

Release Of Acetylcholine ◽

Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice

Behavioural Brain Research ◽

10.1016/j.bbr.2003.09.004 ◽

2004 ◽

Vol 151 (1-2) ◽

pp. 267-276 ◽

Cited By ~ 16

Author(s):

Eun-Joo Shin ◽

Toshitaka Nabeshima ◽

Phil Ho Lee ◽

Won-Ki Kim ◽

Kwang Ho Ko ◽

...

Keyword(s):

Calcium Channel ◽

Bay K 8644 ◽

Central and peripheral effects of the dihydropyridine calcium channel activator BAY K 8644 in the rat

European Journal of Pharmacology ◽

10.1016/0014-2999(89)90089-7 ◽

1989 ◽

Vol 160 (3) ◽

pp. 339-347 ◽

Cited By ~ 34

Author(s):

Anne Bourson ◽

Paul C. Moser ◽

Alma J. Gower ◽

Anis K. Mir

Keyword(s):

Calcium Channel ◽

Bay K 8644 ◽

The calcium channel activator, bay K 8644, enhances K+-evoked efflux of acetylcholine and noradrenaline from rat brain slices

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/bf00498860 ◽

1985 ◽

Vol 331 (1) ◽

pp. 114-116 ◽

Cited By ~ 62

Author(s):

D. N. Middlemiss

Keyword(s):

Calcium Channel ◽

Rat Brain ◽

Brain Slices ◽

Bay K 8644 ◽