calcium channel antagonist
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Scalable Asymmetric Synthesis of MK-8998, a T-Type Calcium Channel Antagonist

2021 ◽  
Author(s):  
Yong-Li Zhong ◽  
Jeffrey C. Moore ◽  
Michael Shevlin ◽  
C. Scott Shultz ◽  
Birgit Kosjek ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Asymmetric Synthesis ◽  
Calcium Channel Antagonist

scholarly journals The T‐type calcium channel antagonist, Z944, reduces spinal excitability and pain hypersensitivity

2021 ◽  
Author(s):  
Erika K. Harding ◽  
Annemarie Dedek ◽  
Robert P. Bonin ◽  
Michael W. Salter ◽  
Terrance P. Snutch ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Antagonist ◽  
Pain Hypersensitivity ◽  
Spinal Excitability

scholarly journals A dendronized polymer variant that facilitates safe delivery of a calcium channel antagonist to the heart

2020 ◽  
Vol 29 ◽  
pp. 102264
Author(s):  
Helena M. Viola ◽  
Ashay A. Shah ◽  
Jessica A. Kretzmann ◽  
Cameron W. Evans ◽  
Marck Norret ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Antagonist ◽  
Safe Delivery ◽  
Dendronized Polymer

Disease-modifying effects of a novel T-type calcium channel antagonist, Z944, in a model of temporal lobe epilepsy

2019 ◽  
Vol 182 ◽  
pp. 101677 ◽  
Author(s):  
Pablo M. Casillas-Espinosa ◽  
Sandy R. Shultz ◽  
Emma L. Braine ◽  
Nigel C. Jones ◽  
Terrance P. Snutch ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Calcium Channel ◽  
Temporal Lobe ◽  
Calcium Channel Antagonist ◽  
Disease Modifying

The T-type calcium channel antagonist, Z944, alters social behavior in Genetic Absence Epilepsy Rats from Strasbourg

2019 ◽  
Vol 361 ◽  
pp. 54-64 ◽  
Author(s):  
Wendie N. Marks ◽  
Nadine K. Zabder ◽  
Stuart M. Cain ◽  
Terrance P. Snutch ◽  
John G. Howland
Keyword(s):  
Social Behavior ◽  
Calcium Channel ◽  
Calcium Channel Antagonist ◽  
Absence Epilepsy

Racemic X-ray structure of L-type calcium channel antagonist Calciseptine prepared by total chemical synthesis

2018 ◽  
Vol 61 (6) ◽  
pp. 702-707 ◽  
Author(s):  
Chen-Chen Chen ◽  
Shuai Gao ◽  
Hua-Song Ai ◽  
Qian Qu ◽  
Chang-Lin Tian ◽  
...  
Keyword(s):  
Chemical Synthesis ◽  
Calcium Channel ◽  
Calcium Channel Antagonist ◽  
X Ray
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