ChemInform Abstract: Synthesis of Diphenyl Phosphonate Analogues of Tyrosine and Tryptophan and Derived Peptides as Chymotrypsin Inhibitors.

ChemInform ◽  
2010 ◽  
Vol 27 (38) ◽  
pp. no-no
Author(s):  
C. BERGIN ◽  
R. HAMILTON ◽  
B. WALKER ◽  
B. J. WALKER
Keyword(s):  
Chymotrypsin Inhibitors

Di- and tripeptide N-alkyl- and N-aralkyl amides as chymotrypsin inhibitors

1988 ◽  
Vol 53 (11) ◽  
pp. 2877-2883 ◽  
Author(s):  
Evžen Kasafírek ◽  
Irena Šutiaková ◽  
Michal Bartík ◽  
Antonín Šturc
Keyword(s):  
Methyl Ethyl ◽  
Competitive Inhibitors ◽  
Inhibition Constants ◽  
Chymotrypsin Inhibitors

Two competitive inhibitors of chymotrypsin, Glt-Ala-Ala-Leu-EtPh and Glt-Ala-Ala-Pro-NH-EtPh, were synthesized and their inhibition constants Ki were determined. The Ki-determination was carried also with a set of peptides of type X-(Ala)nNH-Y, where X is 3-carboxypropionyl- or 4-carboxybutyryl-, n is 2 or 3 and Y is methyl, ethyl, diethyl, isopropyl, propyl, butyl, isobutyl and 2-phenylethyl. Chymotrypsin inhibition was observed only with peptides containing an aralkyl residue whereas peptides with an alkyl are without any effect. Glt-Ala-Ala-Leu-NH-EtPh shows the highest Ki-value (80 μmol l-1).

Trypsin and Chymotrypsin Inhibitors in Insects and Gut Leeches

2002 ◽  
Vol 8 (7) ◽  
pp. 483-491 ◽  
Author(s):  
Liliane Schoofs ◽  
Elke Clynen ◽  
Michel Salzet
Keyword(s):  
Chymotrypsin Inhibitors

Production of extracellular trypsin and chymotrypsin inhibitors by aStreptomyces sp

1989 ◽  
Vol 29 (7) ◽  
pp. 413-417
Author(s):  
Yordanka Kourteva ◽  
Blaga Angelova ◽  
Valya Peretz
Keyword(s):  
Chymotrypsin Inhibitors
Sign in / Sign up

Export Citation Format

Share Document