ChemInform Abstract: Synthesis and Biological Evaluation of Certain Alkenyldiarylmethanes as Anti-HIV-1 Agents Which Act as Non-Nucleoside Reverse Transcriptase Inhibitors.

ChemInform ◽  
2010 ◽  
Vol 27 (48) ◽  
pp. no-no
Author(s):  
M. CUSHMAN ◽  
W. M. GOLEBIEWSKI ◽  
L. GRAHAM ◽  
J. A. TURPIN ◽  
W. G. RICE ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Biological Evaluation ◽  
Reverse Transcriptase Inhibitors ◽  
Nucleoside Reverse Transcriptase Inhibitors ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

Synthesis and biological evaluation of novel quinoxalinone-based HIV-1 reverse transcriptase inhibitors

MedChemComm ◽  
2014 ◽  
Vol 5 (4) ◽  
pp. 441-444 ◽  
Author(s):  
Jie Zhou ◽  
Mingyu Ba ◽  
Bo Wang ◽  
Haibo Zhou ◽  
Jianbo Bie ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Biological Evaluation ◽  
Reverse Transcriptase Inhibitors ◽  
Quinoxalinone Derivatives ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

A series of novel quinoxalinone derivatives were identified as potent anti-HIV-1 agents with IC50 values at 10−8 μmol L−1 level.

Sign in / Sign up

Export Citation Format

Share Document