Facile Reduction of Carboxylic Acids, Esters, Acid Chlorides, Amides and Nitriles to Alcohols or Amines Using NaBH4/BF3×Et2O.

ChemInform ◽  
2004 ◽  
Vol 35 (34) ◽  
Author(s):  
Su-Dong Cho ◽  
Yong-Dae Park ◽  
Jeum-Jong Kim ◽  
J. R. Falck ◽  
Yong-Jin Yoon
Author(s):  
P. I. Alimov ◽  
L. N. Levkova ◽  
L. A. Antokhina ◽  
I. V. Cheplanova

1990 ◽  
Vol 55 (5) ◽  
pp. 1278-1289 ◽  
Author(s):  
Miroslav Protiva ◽  
Vladimír Valenta ◽  
Zdeňka Kopicová ◽  
Juraj Lukáč ◽  
Jiří Holubek ◽  
...  

2-Dimethylaminoethyl esters of 2,2-dimethylpropanoic, heptanoic, octanoic, decanoic, hexadecanoic, cyclopentylacetic, cycloheptylacetic, 2-cyclopentylhexanoic, (4-chlorophenoxy)fumaric, and 2-(4-chlorophenoxy)succinic acid were prepared by reactions of the acid chlorides with 2-dimethylaminoethanol and were transformed to crystalline salts for pharmacological testing. The ester IX (hydrogen fumarate V⁄FB-14 005) was found to antagonize significantly halothan amnesia in rats and the ester X (hydrogen fumarate V⁄FB-14004) proved to be an anticholinergic spasmolytic agent.


ChemInform ◽  
2010 ◽  
Vol 33 (12) ◽  
pp. no-no
Author(s):  
Tsuyoshi Satoh ◽  
Akira Nakamura ◽  
Atsuko Iriuchijima ◽  
Yasumasa Hayashi ◽  
Ko-ichi Kubota

2019 ◽  
Vol 10 (31) ◽  
pp. 7399-7406 ◽  
Author(s):  
Peter H. Huy ◽  
Christelle Mbouhom

Formamide catalysis enables highly cost-efficient amide C–N and ester C–O bond formation through carboxylic acid chlorides as essential intermediates.


Author(s):  
T. P. Vasil'eva ◽  
M. G. Lin'kova ◽  
O. V. Kil'disheva ◽  
I. L. Knunyants

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