ChemInform Abstract: Enantioselective Organocatalytic Michael Addition of Malonates to α,β-Unsaturated Aldehydes in Water.

ChemInform ◽  
2008 ◽  
Vol 39 (31) ◽  
Author(s):  
Anqi Ma ◽  
Shaolin Zhu ◽  
Dawei Ma
Keyword(s):  
Michael Addition ◽  
Unsaturated Aldehydes

Asymmetric Organocatalytic Michael Addition–Cyclization Cascade of Cyclopentane-1,2-dione with Substituted α,β-Unsaturated Aldehydes

Synthesis ◽  
2017 ◽  
Vol 49 (14) ◽  
pp. 3118-3125 ◽  
Author(s):  
Margus Lopp ◽  
Gert Preegel ◽  
Estelle Silm ◽  
Sandra Kaabel ◽  
Ivar Järving ◽  
...  
Keyword(s):  
Michael Addition ◽  
Cascade Reaction ◽  
One Pot ◽  
Unsaturated Aldehydes ◽  
Michael Acceptors

An asymmetric organocatalytic Michael addition–cyclization cascade reaction has been developed using cyclopentane-1,2-dione as a Michael donor and α,β-unsaturated aldehydes as Michael acceptors. Bicyclic hemiacetals were obtained in excellent yields and enantioselectivities. On the basis of the results, a one-pot reaction has been developed to obtain chiral 3-substituted cyclopentane-1,2-diones and substituted dihydropyrans in good yields and excellent enantioselectivity.

ChemInform Abstract: Asymmetric Direct Michael Addition of Acetophenone to α,β-Unsaturated Aldehydes.

ChemInform ◽  
2011 ◽  
Vol 42 (33) ◽  
pp. no-no
Author(s):  
Wenjun Li ◽  
Wenbin Wu ◽  
Juanjuan Yang ◽  
Xinmiao Liang ◽  
Jinxing Ye
Keyword(s):  
Michael Addition ◽  
Unsaturated Aldehydes
Sign in / Sign up

Export Citation Format

Share Document