ChemInform Abstract: Target-Based Drug Discovery: The Emerging Success of Frontal Affinity Chromatography Coupled to Mass Spectrometry

Frontal affinity chromatography–mass spectrometry assay technology for multiple stages of drug discovery: applications of a chromatographic biosensor

Analytical Biochemistry ◽

10.1016/s0003-2697(03)00193-3 ◽

2003 ◽

Vol 319 (1) ◽

pp. 1-12 ◽

Cited By ~ 49

Author(s):

Nora W.C Chan ◽

Darren F Lewis ◽

Philip J Rosner ◽

Michele A Kelly ◽

David C Schriemer

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Affinity Chromatography ◽

Chromatography Mass Spectrometry ◽

Multiple Stages ◽

Mass Spectrometry Assay

Global Kinase Screening. Applications of Frontal Affinity Chromatography Coupled to Mass Spectrometry in Drug Discovery

Analytical Chemistry ◽

10.1021/ac048716q ◽

2005 ◽

Vol 77 (5) ◽

pp. 1268-1274 ◽

Cited By ~ 32

Author(s):

Jacek J. Slon-Usakiewicz ◽

Jin-Rui Dai ◽

William Ng ◽

J. Estelle Foster ◽

Eugen Deretey ◽

...

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Affinity Chromatography ◽

Kinase Screening

Target-Based Drug Discovery: the Emerging Success of Frontal Affinity Chromatography Coupled to Mass Spectrometry

ChemMedChem ◽

10.1002/cmdc.200800436 ◽

2009 ◽

Vol 4 (6) ◽

pp. 905-916 ◽

Cited By ~ 32

Author(s):

Enrica Calleri ◽

Caterina Temporini ◽

Gabriele Caccialanza ◽

Gabriella Massolini

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Affinity Chromatography ◽

Frontal Affinity Chromatography Coupled to Mass Spectrometry: An Effective Method for Kd Determination and Screening of α‐Gal Derivatives Binding to Anti‐Gal Antibodies (IgG)

Journal of Carbohydrate Chemistry ◽

10.1081/car-120025323 ◽

2003 ◽

Vol 22 (6) ◽

pp. 347-376 ◽

Cited By ~ 6

Author(s):

Jianqiang Wang ◽

Boyan Zhang ◽

Jianwen Fang ◽

Keiko Sujino ◽

Hong Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Affinity Chromatography ◽

Ligand-Macromolecular Interactions in Drug Discovery - Methods in Molecular Biology ◽

Application of Frontal Affinity Chromatography with Mass Spectrometry (FAC–MS) for Stereospecific Ligand–Macromolecule Interaction, Detection and Screening

10.1007/978-1-60761-244-5_14 ◽

2009 ◽

pp. 219-230 ◽

Cited By ~ 1

Author(s):

Jacek J. Slon-Usakiewicz ◽

Peter Redden

Keyword(s):

Mass Spectrometry ◽

Affinity Chromatography ◽

Interaction Detection ◽

Frontal affinity chromatography—mass spectrometry

Nature Protocols ◽

10.1038/nprot.2007.262 ◽

2007 ◽

Vol 2 (8) ◽

pp. 1907-1917 ◽

Cited By ~ 36

Author(s):

Ella S M Ng ◽

Nora WC Chan ◽

Darren F Lewis ◽

Ole Hindsgaul ◽

David C Schriemer

Keyword(s):

Mass Spectrometry ◽

Affinity Chromatography ◽

Chromatography Mass Spectrometry

Rapid determination of the binding affinity and specificity of the mushroom Polyporus squamosus lectin using frontal affinity chromatography coupled to electrospray mass spectrometry

Glycobiology ◽

10.1093/glycob/11.2.141 ◽

2001 ◽

Vol 11 (2) ◽

pp. 141-147 ◽

Cited By ~ 40

Author(s):

B. Zhang ◽

M. M. Palcic ◽

H. Mo ◽

I. J. Goldstein ◽

O. Hindsgaul

Keyword(s):

Mass Spectrometry ◽

Affinity Chromatography ◽

Binding Affinity ◽

Electrospray Mass Spectrometry ◽

Rapid Determination ◽

Polyporus Squamosus

Monolithic membrane-receptor columns: Optimization of column performance for frontal affinity chromatography/mass spectrometry applications

Analytica Chimica Acta ◽

10.1016/j.aca.2005.12.062 ◽

2006 ◽

Vol 561 (1-2) ◽

pp. 107-118 ◽

Cited By ~ 24

Author(s):

Travis R. Besanger ◽

Richard J. Hodgson ◽

Domitille Guillon ◽

John D. Brennan

Keyword(s):

Mass Spectrometry ◽

Affinity Chromatography ◽

Membrane Receptor ◽

Chromatography Mass Spectrometry ◽

Column Performance

Mass Spectrometry in Medicinal Chemistry - Methods and Principles in Medicinal Chemistry ◽

Frontal Affinity Chromatography – Mass Spectrometry for Ligand Discovery and Characterization

10.1002/9783527610907.ch6 ◽

2007 ◽

pp. 217-246 ◽

Cited By ~ 5

Author(s):

Nora Chan ◽

Darren Lewis ◽

Michele Kelly ◽

Ella S. M. Ng ◽

David C. Schriemer

Keyword(s):

Mass Spectrometry ◽

Affinity Chromatography ◽

Chromatography Mass Spectrometry ◽

Ligand Discovery

Methods in Enzymology - Recognition of Carbohydrates in Biological Systems, Part A: General Procedures ◽

Evaluating Carbohydrate–Protein Binding Interactions Using Frontal Affinity Chromatography Coupled to Mass Spectrometry

10.1016/s0076-6879(03)01026-7 ◽

2003 ◽

pp. 369-376 ◽

Cited By ~ 5

Author(s):

Monica M Palcic ◽

Boyan Zhang ◽

Xiangping Qian ◽

Brian Rempel ◽

Ole Hindsgaul

Keyword(s):

Mass Spectrometry ◽

Protein Binding ◽

Affinity Chromatography ◽

Binding Interactions ◽