ChemInform Abstract: Boron-Catalyzed Direct Aldol Reactions of Pyruvic Acids.

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Aldol reactions of amide enolates formed by addition of nitronates to acrylamides proceeded with catalytic amounts of KOH in DMSO.


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A novel amphiphilic acylguanidine organocatalyst using intramolecular hydrogen bonding as a key structural motif is efficient for asymmetric aldol reactions of ketones in water at neutral pH.


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