Evaluation of the macrocyclic antibiotic vancomycin as a chiral selector for capillary electrophoresis

Chirality ◽  
1994 ◽  
Vol 6 (6) ◽  
pp. 496-509 ◽  
Author(s):  
Daniel W. Armstrong ◽  
Kimber L. Rundlett ◽  
Jing-Ran Chen
Keyword(s):  
Capillary Electrophoresis ◽  
Chiral Selector ◽  
Macrocyclic Antibiotic

Evaluation of a New Macrocyclic Antibiotic as a Chiral Selector for Use in Capillary Electrophoresis

1997 ◽  
Vol 20 (6) ◽  
pp. 887-898 ◽  
Author(s):  
V. Scott Sharp ◽  
Donald S. Risley ◽  
Sharon McCarthy ◽  
Bret E. Huff ◽  
Mark A. Strege
Keyword(s):  
Capillary Electrophoresis ◽  
Chiral Selector ◽  
Macrocyclic Antibiotic

scholarly journals Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3527
Author(s):  
Ali Fouad ◽  
Adel A. Marzouk ◽  
Montaser Sh. A. Shaykoon ◽  
Samy M. Ibrahim ◽  
Sobhy M. El-Adl ◽  
...  
Keyword(s):  
Glycidyl Methacrylate ◽  
Chiral Stationary Phase ◽  
Reversed Phase ◽  
Chiral Selector ◽  
Antifungal Drugs ◽  
Organic Polymer ◽  
Rp Hplc ◽  
Macrocyclic Antibiotic ◽  
Adrenergic Blockers ◽  
H1 Blockers

Daptomycin, a macrocyclic antibiotic, is here used as a new chiral selector in preparation of chiral stationary phase (CSP) in a recently prepared polymer monolithic capillary. The latter is prepared using the copolymerization of the monomers glycidyl methacrylate (GMA) and ethylene glycol dimethacrylate (EGDMA) in the presence of daptomycin in water. Under reversed phase conditions (RP), the prepared capillaries were tested for the enantioselective nanoliquid chromatographic separation of fifty of the racemic drugs of different pharmacological groups, such as adrenergic blockers, H1-blockers, NSAIDs, antifungal drugs, and others. Baseline separation was attained for many drugs under RP-HPLC. Daptomycin expands the horizon of chiral selectors in HPLC.

Determination of enantiomeric excess for 2,3-dihydroxy-3-phenylpropionate compounds by capillary electrophoresis using hydroxypropyl-β-cyclodextrin as chiral selector

Chirality ◽  
2007 ◽  
Vol 19 (5) ◽  
pp. 380-385 ◽  
Author(s):  
Yan Zhao ◽  
Xing-Bin Yang ◽  
Qiao-Feng Wang ◽  
Peng-Juan Nan ◽  
Ying Jin ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Enantiomeric Excess ◽  
Chiral Selector

Fast enantiomeric separation of propranolol by affinity capillary electrophoresis using human serum albumin as chiral selector: application to quality control of pharmaceuticals

2004 ◽  
Vol 507 (2) ◽  
pp. 171-178 ◽  
Author(s):  
Juan José Martı́nez-Pla ◽  
Yolanda Martı́n-Biosca ◽  
Salvador Sagrado ◽  
Rosa Marı́a Villanueva-Camañas ◽  
Marı́a José Medina-Hernández
Keyword(s):  
Quality Control ◽  
Capillary Electrophoresis ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Enantiomeric Separation ◽  
Chiral Selector ◽  
Affinity Capillary Electrophoresis
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