Model‐Informed Drug Development Approach to Expedite Approval: Case of Alectinib in First‐Line Anaplastic Lymphoma Kinase + Non‐Small Cell Lung Cancer

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1340 ◽

2019 ◽

Vol 105 (4) ◽

pp. 826-828

Author(s):

Peter N. Morcos ◽

Jiang Liu ◽

Gideon M. Blumenthal ◽

Hong Zhao

Keyword(s):

Lung Cancer ◽

Drug Development ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

Development Approach

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The use of alectinib in the first-line treatment of anaplastic lymphoma kinase-positive non-small-cell lung cancer

Future Oncology ◽

10.2217/fon-2018-0027 ◽

2018 ◽

Vol 14 (18) ◽

pp. 1875-1882 ◽

Author(s):

Shirish M Gadgeel

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Line Treatment ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

First Line Treatment

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The Pan-Immune-Inflammation Value predicts the survival of patients with anaplastic lymphoma kinase-positive non-small cell lung cancer treated with first-line ALK inhibitor

Translational Oncology ◽

10.1016/j.tranon.2021.101338 ◽

2022 ◽

Vol 17 ◽

pp. 101338

Author(s):

Xinru Chen ◽

Xiangchan Hong ◽

Gang Chen ◽

Jinhui Xue ◽

Jie Huang ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

Alk Inhibitor ◽

Immune Inflammation

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What is the optimal first-line treatment for advanced anaplastic lymphoma kinase-rearranged non-small cell lung cancer?

Journal of Thoracic Disease ◽

10.21037/jtd.2017.04.43 ◽

2017 ◽

Vol 9 (5) ◽

pp. E447-E450

Author(s):

Ikuo Sekine

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Line Treatment ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

First Line Treatment

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Crizotinib in patients with anaplastic lymphoma kinase-positive advanced non-small cell lung cancer versus chemotherapy as a first-line treatment

10.1186/s12885-017-3720-8 ◽

2018 ◽

Vol 18 (1) ◽

Author(s):

Jianya Zhou ◽

Jing Zheng ◽

Xiaochen Zhang ◽

Jing Zhao ◽

Yanping Zhu ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Line Treatment ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

First Line Treatment

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Cost Effectiveness of Ceritinib and Alectinib Versus Crizotinib in First-Line Anaplastic Lymphoma Kinase-Positive Advanced Non-small-cell Lung Cancer

Clinical Drug Investigation ◽

10.1007/s40261-019-00880-8 ◽

2019 ◽

Vol 40 (2) ◽

pp. 183-189 ◽

Author(s):

Hongchao Li ◽

Lei Lai ◽

Bin Wu

Keyword(s):

Lung Cancer ◽

Cost Effectiveness ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma

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Cost-Effectiveness of Crizotinib, Ceritinib, and Alectinib as First-Line Treatments for Anaplastic Lymphoma Kinase-Positive (ALK+) Metastatic Non-Small Cell Lung Cancer

Value in Health ◽

10.1016/j.jval.2018.04.208 ◽

2018 ◽

Vol 21 ◽

pp. S32-S33

Author(s):

S Xuan ◽

J Ma

Keyword(s):

Lung Cancer ◽

Cost Effectiveness ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma

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P84.08 First-line Brigatinib in Anaplastic Lymphoma Kinase-positive Non-small Cell Lung Cancer: A Network Meta-Analysis

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2021.01.1207 ◽

2021 ◽

Vol 16 (3) ◽

pp. S659-S660

Author(s):

H. Lin ◽

A. Cichewicz ◽

B. Neupane ◽

Y. Wu ◽

L. Vinals ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Meta Analysis ◽

Small Cell Lung ◽

Anaplastic Lymphoma

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PCN140 - COST-EFFECTIVENESS ANALYSIS OF ALECTINIB VS CRIZOTINIB IN FIRST LINE ANAPLASTIC LYMPHOMA KINASE POSITIVE ADVANCED NON-SMALL CELL LUNG CANCER IN PORTUGAL

Value in Health ◽

10.1016/j.jval.2018.09.223 ◽

2018 ◽

Vol 21 ◽

pp. S38

Author(s):

V. Soares ◽

P. Orfanos ◽

C. Pereira

Keyword(s):

Lung Cancer ◽

Cost Effectiveness ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma ◽

Effectiveness Analysis

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Cost Effectiveness of Alectinib vs. Crizotinib in First-Line Anaplastic Lymphoma Kinase-Positive Advanced Non-Small-Cell Lung Cancer

PharmacoEconomics ◽

10.1007/s40273-018-0625-6 ◽

2018 ◽

Vol 36 (4) ◽

pp. 495-504 ◽

Author(s):

Josh J. Carlson ◽

Kangho Suh ◽

Panos Orfanos ◽

William Wong

Keyword(s):

Lung Cancer ◽

Cost Effectiveness ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma

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P1.13-06 First-Line Lorlatinib Versus Crizotinib for Advanced Anaplastic Lymphoma Kinase-Positive (ALK+) Non-Small Cell Lung Cancer

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2018.08.863 ◽

2018 ◽

Vol 13 (10) ◽

pp. S584 ◽

Author(s):

A. Shaw ◽

T. Bauer ◽

T. Takahashi ◽

C. Baik ◽

Y. Goto ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Anaplastic Lymphoma Kinase ◽

Small Cell Lung ◽

Anaplastic Lymphoma

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