Expression ofFoxi3is regulated by ectodysplasin in skin appendage placodes

2013 ◽  
Vol 242 (6) ◽  
pp. 593-603 ◽  
Author(s):  
Vera Shirokova ◽  
Maria Jussila ◽  
Marjo K. Hytönen ◽  
Nina Perälä ◽  
Cord Drögemüller ◽  
...  
Keyword(s):  
Skin Appendage

scholarly journals p63 in Skin Appendage Development

Cell Cycle ◽  
2007 ◽  
Vol 6 (3) ◽  
pp. 285-290 ◽  
Author(s):  
Marja L. Mikkola
Keyword(s):  
Appendage Development ◽  
Skin Appendage

scholarly journals Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog(Atelerix albiventris)

2020 ◽  
Author(s):  
Hui-Ming Li ◽  
Bi-Ze Yang ◽  
Xiu-Juan Zhang ◽  
Hai-Ying Jiang ◽  
Lin-Miao Li ◽  
...  
Keyword(s):  
Genetic Basis ◽  
Enrichment Analysis ◽  
Differentially Expressed ◽  
Mammal Species ◽  
Appendage Development ◽  
Skin Appendage ◽  
Hair Type ◽  
Spine Development ◽  
Skin Appendages ◽  
Development And Differentiation

Abstract Background: The expression of hair features is an evolutionary adaptation resulting from interactions between many organisms and their environment. Elucidation of the mechanisms that underlie the expression of such traits is a topic in evolutionary biology research; however, the genetic basis of skin appendage development and differentiation remains poorly understood. Therefore, we assessed the de novo transcriptome of the hedgehog ( Atelerix albiventris ) at three developmental stages and compared gene expression profiles between abdomen hair and dorsal spine tissues. Results: We identified 328,576 unigenes in our transcriptome, among which 3,598 were differentially expressed between hair- and spine-type tissues. We identified 3 keratin genes related to hair and spine development through comparative analysis of tissues before and after growth of skin appendages. Dorsal and abdomen skin tissues 5 days after birth were compared and the resulting differentially expressed genes (DEGs) were mainly enriched in keratin filament, intermediate filament, epithelium cell differentiation, and epidermis development based on GO enrichment analysis, and tight junction, p53, and cell cycle signaling pathways based on KEGG enrichment analysis. Expression variations of MBP8, SFN, Wnt10, KRT1 , and KRT2 may be the main factors regulating hair and spine differentiation for the hedgehog. Strikingly, DEGs in hair-type tissues were also significantly enriched in immune-related terms and pathways with hair-type tissues exhibiting more upregulated immune genes than spine-type tissues. Thus, we propose that spine development was an adaptation that provided protection against injuries or stress and reduced hedgehog vulnerability to infection. Conclusion: Our study provided a list of potential genes involved in the regulation of skin appendage development and differentiation in A. albiventris . This is the first transcriptome survey of hair traits for a non-model mammal species, and the candidate genes provided here may provide valuable information for further studies of skin appendages and skin disorder treatments.

scholarly journals Five New CYLD Mutations in Skin Appendage Tumors and Evidence that Aspartic Acid 681 in CYLD Is Essential for Deubiquitinase Activity

2008 ◽  
Vol 128 (3) ◽  
pp. 587-593 ◽  
Author(s):  
Stéphanie Almeida ◽  
Caroline Maillard ◽  
Peter Itin ◽  
Daniel Hohl ◽  
Marcel Huber
Keyword(s):  
Aspartic Acid ◽  
Skin Appendage

scholarly journals Photodynamic Therapy and Skin Appendage Disorders: A Review

2016 ◽  
Vol 2 (3-4) ◽  
pp. 166-176 ◽  
Author(s):  
Matteo Megna ◽  
Gabriella Fabbrocini ◽  
Claudio Marasca ◽  
Giuseppe Monfrecola
Keyword(s):  
Photodynamic Therapy ◽  
Skin Appendage

scholarly journals Avian Integument Provides Multiple Possibilities to Analyse Different Phases of Skin Appendage Morphogenesis

1999 ◽  
Vol 4 (3) ◽  
pp. 333-337 ◽  
Author(s):  
Chia-Wei Janet Chen ◽  
Cheng-Ming Chuong
Keyword(s):  
Skin Appendage

scholarly journals Acknowledgement to Referees for Skin Appendage Disorders 2017

2017 ◽  
Vol 3 (4) ◽  
pp. 226-226
Keyword(s):  
Skin Appendage

Genetic basis of skin appendage development

2007 ◽  
Vol 18 (2) ◽  
pp. 225-236 ◽  
Author(s):  
Marja L. Mikkola
Keyword(s):  
Genetic Basis ◽  
Appendage Development ◽  
Skin Appendage

Apocrine skin appendage carcinoma. Real clinical practice

Pharmateca ◽  
2020 ◽  
Vol 11_2020 ◽  
pp. 81-87
Author(s):  
Yu.V. Vakhabova Vakhabova ◽  
M.A. Polyak Polyak ◽  
E.O. Ignatova Ignatova ◽  
V.A. Derzhavin Derzhavin ◽  
O.A. Anurova Anurova ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Skin Appendage ◽  
Real Clinical Practice

scholarly journals Early Events During Avian Skin Appendage Regeneration: Dependence on Epithelial-Mesenchymal Interaction and order of Molecular Reappearance

1996 ◽  
Vol 107 (4) ◽  
pp. 639-646 ◽  
Author(s):  
Cheng-Ming Chuong ◽  
Randall B. Widelitz ◽  
Sheree Ting-Berreth ◽  
Ting-Xin Jiang
Keyword(s):  
Skin Appendage

Skin appendage involvement in anal intraepithelial neoplasia

1997 ◽  
Vol 84 (5) ◽  
pp. 675-678 ◽  
Author(s):  
P. P. Skinner ◽  
O. A. Ogunbiyi ◽  
J. H. Scholefield ◽  
R. D. Start ◽  
J. H. F. Smith ◽  
...  
Keyword(s):  
Intraepithelial Neoplasia ◽  
Anal Intraepithelial Neoplasia ◽  
Skin Appendage
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