scholarly journals Combination therapy with radiation and hyperthermia‐induced clinical complete response of small cell carcinoma of prostate

2022 ◽  
Author(s):  
Noriyasu Kawai ◽  
Takashi Nagai ◽  
Aya Naiki‐Ito ◽  
Keitaro Iida ◽  
Toshiki Etani ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Complete Response ◽  
Small Cell ◽  
Clinical Complete Response

scholarly journals Complete Response of Recurrent Small Cell Carcinoma of the Uterine Cervix to Paclitaxel, Carboplatin, and Bevacizumab Combination Therapy

2020 ◽  
Vol 13 (1) ◽  
pp. 373-378 ◽  
Author(s):  
Yuri Nakao ◽  
Satoshi Tamauchi ◽  
Nobuhisa Yoshikawa ◽  
Shiro Suzuki ◽  
Hiroaki Kajiyama ◽  
...  
Keyword(s):  
Lymph Node ◽  
Combination Therapy ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Uterine Cervix ◽  
Posterior Wall ◽  
Complete Response ◽  
Uterine Sarcoma ◽  
Small Cell ◽  
Lymph Node Sampling

We report a case of recurrent small cell carcinoma of the uterine cervix that showed a complete response to paclitaxel, carboplatin, and bevacizumab (TC + Bev) combination therapy. Small cell carcinoma of the uterine cervix is extremely rare, with an incidence of only 1.3% in Japan, and a poor outcome. The patient was a 62-year-old woman with a chief complaint of irregular vaginal bleeding. Magnetic resonance imaging showed a 10-cm irregular mass from the uterine corpus’s posterior wall to the cervix. Abdominal total hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymph node sampling were performed for suspected uterine sarcoma. Histopathological findings revealed small cell carcinoma with lymph node metastasis. Although 6 cycles of etoposide + cisplatin were performed, para-aortic lymph node recurrence was found 3 months after chemotherapy. Subsequently, the patient received 8 cycles of TC + Bev, which eliminated the metastases. The patient is currently alive at 24 months.

Initial Combination Therapy with YAG Laser Photoresection and Irradiation for Inoperable Non-Small Cell Carcinoma of the Lung

CHEST Journal ◽  
1986 ◽  
Vol 89 (6) ◽  
pp. 782-785 ◽  
Author(s):  
Michael S. Eichenhom ◽  
Paul A. Kvale ◽  
Veronica M. Miks ◽  
H. Gunter Seydel ◽  
Bruce Horowitz ◽  
...  
Keyword(s):  
Combination Therapy ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Yag Laser ◽  
Initial Combination Therapy ◽  
Initial Combination

scholarly journals Primary Small Cell Carcinoma of the Vagina

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Rafael Oliveira ◽  
Mayra Coelho Bócoli ◽  
João Carlos Saldanha ◽  
Eddie Fernando Candido Murta ◽  
Rosekeila Simões Nomelini
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Distant Metastases ◽  
Complete Response ◽  
Undifferentiated Carcinoma ◽  
Vaginal Wall ◽  
Small Cell ◽  
Complete Regression ◽  
Small Cell Undifferentiated Carcinoma ◽  
Upper Third

The primary small cell carcinoma of the vagina is rare, and it is a highly aggressive malignancy with no consensus regarding the treatment of this tumor. The survival rate for patients treated in the early stages is around two years. We related the case report of a patient of 41 years with a vegetative and necrotic lesion in left vaginal wall, in middle and upper third, and involvement of parametrium in its proximal third and medium third. A biopsy showed a small cell undifferentiated carcinoma composed of epithelial cells with round nuclei, oval or elongated, hyperchromatic nuclei, with little distinct nucleoli, and scarce cytoplasm. Immunohistochemistry showed positivity for AE1/AE3, CD57, and chromogranin A. The patient received 6 cycles of chemotherapy with cisplatin and etoposide and radiotherapy, achieving complete response, with complete regression of the lesion. The patient had no sign of tumor recurrence and locoregional or distant metastases after 5 months of followup.

Complete response of esophageal small cell carcinoma amrubicin treatment

2013 ◽  
Vol 19 (4) ◽  
pp. 770-775 ◽  
Author(s):  
Eijiro Nagasaki ◽  
Masami Yuda ◽  
Yuichiro Tanishima ◽  
Yasuhiro Arakawa ◽  
Kazuma Kobayashi ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Complete Response ◽  
Small Cell

Metastatic small cell carcinoma of the endometrium: prolonged remission and possible cure following chemotherapy

1994 ◽  
Vol 4 (2) ◽  
pp. 127-130 ◽  
Author(s):  
R. W. Hunter ◽  
M. Buck ◽  
I. G. Hammond ◽  
K. E. Williams
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Advanced Disease ◽  
Neuron Specific Enolase ◽  
Complete Response ◽  
Small Cell ◽  
Response To Treatment ◽  
Short Survival ◽  
Response To Chemotherapy ◽  
Serum Neuron Specific Enolase

A 54-year-old woman with inoperable metastatic small cell carcinoma (SCC) of the endometrium was treated with cisplatin and etoposide chemotherapy on the basis of the histologic similarity to pulmonary SCC. The response to treatment was monitored using serum neuron specific enolase (NSE) levels. A complete remission was obtained with resolution of symptoms and disappearance of the mass. The patient is alive and well 4½ years later. Considering the aggressive behavior and short survival usually associated with this tumor and the presence of such advanced disease, a complete response to chemotherapy was unexpected. It would appear that chemotherapy should always be considered in the management of metastatic endometrial SCC, even in the presence of large-volume disease.

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