Synthesis of [3H]tert-butyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4h-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a selective, high affinity ligand for the diazepam insensitive (DI) subtype of the benzodiazepine receptor

Zi-Qiang Gu; Brian R. de Costa; Garry Wong; Kenner C. Rice; Phil Skolnick

doi:10.1002/jlcr.2580311213

Synthesis of [3H]tert-butyl 8-chloro-5,6-dihydro-5-methyl-6-oxo-4h-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a selective, high affinity ligand for the diazepam insensitive (DI) subtype of the benzodiazepine receptor

Journal of Labelled Compounds and Radiopharmaceuticals ◽

10.1002/jlcr.2580311213 ◽

1992 ◽

Vol 31 (12) ◽

pp. 1049-1055 ◽

Cited By ~ 7

Author(s):

Zi-Qiang Gu ◽

Brian R. de Costa ◽

Garry Wong ◽

Kenner C. Rice ◽

Phil Skolnick

Keyword(s):

Benzodiazepine Receptor ◽

Tert Butyl ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

6,3'-Dinitroflavone, a novel high affinity ligand for the benzodiazepine receptor with potent anxiolytic properties

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/0960-894x(95)00464-5 ◽

1995 ◽

Vol 5 (22) ◽

pp. 2717-2720 ◽

Cited By ~ 28

Author(s):

Mariel Marder ◽

Haydee Viola ◽

Cristina Wasowski ◽

Claudia Wolfman ◽

Peter G. Waterman ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

Synthesis of .beta.-carboline-benzodiazepine hybrid molecules: use of the known structural requirements for benzodiazepine and .beta.-carboline binding in designing a novel, high-affinity ligand for the benzodiazepine receptor

Journal of Medicinal Chemistry ◽

10.1021/jm00390a023 ◽

1987 ◽

Vol 30 (7) ◽

pp. 1248-1254 ◽

Cited By ~ 18

Author(s):

Robert H. Dodd ◽

Catherine Ouannes ◽

Marie Claude Potier ◽

Lia Prado de Carvalho ◽

Jean Rossier ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Structural Requirements ◽

High Affinity ◽

Affinity Ligand ◽

Hybrid Molecules ◽

High Affinity Ligand

Download Full-text

Characteristics of the Association of Brotizolam, a Thieno-Triazolo Diazepine Derivative, with the Benzodiazepine Receptor: A Selective and High Affinity Ligand of the Central Type I Benzodiazepine Receptor.

The Japanese Journal of Pharmacology ◽

10.1254/jjp.59.387 ◽

1992 ◽

Vol 59 (3) ◽

pp. 387-391 ◽

Cited By ~ 5

Author(s):

Masaaki Hirouchi ◽

Hiroshi Mizutani ◽

Yasuko Kohno ◽

Kinya Kuriyama

Keyword(s):

Benzodiazepine Receptor ◽

Type I ◽

Central Type ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

Neurochemical studies on brotizolam as a high affinity ligand for benzodiazepine receptor

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)49041-0 ◽

1992 ◽

Vol 58 ◽

pp. 181

Author(s):

Masaaki Hirouchi ◽

Hiroshi Mizutani ◽

Kinya Kuriyama

Keyword(s):

Benzodiazepine Receptor ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

ChemInform Abstract: Synthesis of β-Carboline-Benzodiazepine Hybrid Molecules: Use of the Known Structural Requirements for Benzodiazepine and β-Carboline Binding in Designing a Novel, High-Affinity Ligand for the Benzodiazepine Receptor.

ChemInform ◽

10.1002/chin.198750244 ◽

1987 ◽

Vol 18 (50) ◽

Author(s):

R. H. DODD ◽

C. OUANNES ◽

M.-C. POTIER ◽

L. PRADO DE CARVALHO ◽

J. ROSSIER ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

Structural Requirements ◽

High Affinity ◽

Affinity Ligand ◽

Hybrid Molecules ◽

High Affinity Ligand

Download Full-text

Characteristics of the Association of Brotizolam, a Thieno-Triazolo Diazepine Derivative, with the Benzodiazepine Receptor: A Selective and High Affinity Ligand of the Central Type I Benzodiazepine Receptor

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)37637-1 ◽

1992 ◽

Vol 59 (3) ◽

pp. 387-391

Author(s):

Masaaki Hirouchi ◽

Hiroshi Mizutani ◽

Yasuko Kohno ◽

Kinya Kuriyama

Keyword(s):

Benzodiazepine Receptor ◽

Type I ◽

Central Type ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

ChemInform Abstract: 6,3′-Dinitroflavone, a Novel High Affinity Ligand for the Benzodiazepine Receptor with Potent Anxiolytic Properties.

ChemInform ◽

10.1002/chin.199612158 ◽

2010 ◽

Vol 27 (12) ◽

pp. no-no

Author(s):

M. MARDER ◽

H. VIOLA ◽

C. WASOWSKI ◽

C. WOLFMAN ◽

P. G. WATERMAN ◽

...

Keyword(s):

Benzodiazepine Receptor ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

Faculty Opinions recommendation of Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1018184.207692 ◽

2004 ◽

Author(s):

Marek Mlodzik

Keyword(s):

Inner Ear ◽

Vascular Development ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

Faculty Opinions recommendation of Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718020257.793478725 ◽

2013 ◽

Author(s):

Shigekazu Nagata

Keyword(s):

Cyclic Gmp ◽

High Affinity ◽

Affinity Ligand ◽

High Affinity Ligand

Download Full-text

Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding. Construction and analysis of chimeric N-formyl peptide receptors.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)46825-6 ◽

1993 ◽

Vol 268 (24) ◽

pp. 18167-18175 ◽

Cited By ~ 3

Author(s):

O. Quehenberger ◽

E.R. Prossnitz ◽

S.L. Cavanagh ◽

C.G. Cochrane ◽

R.D. Ye

Keyword(s):

Ligand Binding ◽

Formyl Peptide Receptor ◽

Peptide Receptors ◽

Formyl Peptide Receptors ◽

Peptide Receptor ◽

High Affinity ◽

Affinity Ligand ◽

Formyl Peptide ◽

Multiple Domains ◽

High Affinity Ligand

Download Full-text