Studies on Micellar Behavior of PEO-PBO or PEO-PBO-PEO Copolymers, or Surface Active Amphiphilic Ionic Liquids in Aqueous Media and Exploration of the Micellar Solutions for Solubilization of Dexamethasone and its Delayed Release

2018 ◽  
Vol 21 (1) ◽  
pp. 65-79 ◽  
Author(s):  
Nandhibatla V. Sastry ◽  
Dipak K. Singh ◽  
Pooja A. Trivedi
2014 ◽  
Vol 428 ◽  
pp. 267-275 ◽  
Author(s):  
K. Srinivasa Rao ◽  
Praveen Singh Gehlot ◽  
Tushar J. Trivedi ◽  
Arvind Kumar

2013 ◽  
Vol 68 (10) ◽  
pp. 1129-1137 ◽  
Author(s):  
Anna K. Ressmann ◽  
Ronald Zirbs ◽  
Martin Pressler ◽  
Peter Gaertner ◽  
Katharina Bica

We present the application of ionic liquid-aqueous micellar solutions as isolation media for the pharmaceutically active ingredient piperine from black pepper. Several surface-active ionic liquids including a biodegradable betaine derivative were used for the extraction of piperine, and a strong correlation between extraction yield and the critical micelle concentration of the respective ionic liquid was found. A scaled strategy for the isolation of piperine was developed that allowed recovery and recycling of the aqueous ionic liquid micellar solution for five runs without any loss in extraction efficiency.


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