Recent improvement in survival outcomes and reappraisal of prognostic factors in pediatric living donor liver transplantation

2021 ◽  
Author(s):  
Seak Hee Oh ◽  
In Sook Jeong ◽  
Dae Yeon Kim ◽  
Jung‐Man Namgoong ◽  
Won Kyoung Jhang ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prognostic Factors ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Survival Outcomes ◽  
Donor Liver ◽  
Recent Improvement ◽  
Donor Liver Transplantation ◽  
Improvement In Survival

scholarly journals Prognostic factors affecting survival after recurrence in adult living donor liver transplantation for hepatocellular carcinoma

2010 ◽  
Vol 16 (5) ◽  
pp. 678-684 ◽  
Author(s):  
Woo Young Shin ◽  
Kyung-Suk Suh ◽  
Hae Won Lee ◽  
Joohyun Kim ◽  
Taehoon Kim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Prognostic Factors ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Factors Affecting ◽  
Donor Liver Transplantation

Prognostic Factors Affecting Survival at Recurrence of Hepatocellular Carcinoma After Living-Donor Liver Transplantation

2013 ◽  
Vol 96 (11) ◽  
pp. 1008-1012 ◽  
Author(s):  
Norifumi Harimoto ◽  
Ken Shirabe ◽  
Hidekazu Nakagawara ◽  
Takeo Toshima ◽  
Yo-ichi Yamashita ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Prognostic Factors ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Factors Affecting ◽  
Donor Liver Transplantation

scholarly journals Living Donor Liver Transplantation: The Optimal Curative Treatment for Hepatocellular Carcinoma Even Beyond Milan Criteria

2021 ◽  
Vol 28 ◽  
pp. 107327482110119
Author(s):  
Altan Alim ◽  
Yalcin Erdogan ◽  
Murat Dayangac ◽  
Yildiray Yuzer ◽  
Yaman Tokat ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Prognostic Factors ◽  
Vascular Invasion ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Alpha Fetoprotein ◽  
Milan Criteria ◽  
Donor Liver ◽  
Donor Liver Transplantation

Introduction: Liver transplantation offers the most reasonable expectation for curative treatment for hepatocellular carcinoma. Living-donor liver transplantation represents a treatment option, even in patients with extended Milan criteria. This study aimed to evaluate the outcomes of hepatocellular carcinoma patients, particularly those extended Milan criteria. Materials and Patients: All HCC patients who received liver transplant for HCC were included in this retrospective study. Clinical characteristics including perioperative data and survival data (graft and patient) were extracted from records. Univariate and multivariate analyses was performed to identify significant prognostic factors for survival, postoperative complications and recurrence. Results: Two-hundred and two patients were included. The median age was 54.8 years (IQR 53-61). Fifty-one patients (25.3%) underwent deceased donors liver transplantation and 151 patients (74.7%) underwent living donor liver transplantation. Perioperative mortality rate was 5.9% (12 patients). Recurrent disease occurred in 43 patients (21.2%). The overall 1-year and 5-year survival rates were 90.7% and 75.6%, respectively. Significant differences between patients beyond Milan criteria compared to those within Milan criteria were not found. Alpha-fetoprotein level >300 ng/mL, vascular invasion, and bilobar tumor lesions were independent negative prognostic factors for survival. Conclusion: Liver transplantation is the preferred treatment for hepatocellular carcinoma and it has demonstrated an excellent potential to cure even in patients with beyond Milan criteria. This study shows that the Milan criteria alone are not sufficient to predict survival after transplantation. The independent parameters for survival prediction are Alpha-Fetoprotein-value and status of vascular invasion.

The Significant Prognostic Factors in Prolonged Intensive/High Care Unit Stay After Living Donor Liver Transplantation

2021 ◽  
Author(s):  
Shohei Yoshiya ◽  
Noboru Harada ◽  
Takahiro Tomiyama ◽  
Kazuki Takeishi ◽  
Takeo Toshima ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prognostic Factors ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
High Care

Prognostic Factors Predicting Poor Outcome in Living-Donor Liver Transplantation for Fulminant Hepatic Failure

2017 ◽  
Vol 49 (5) ◽  
pp. 1118-1122 ◽  
Author(s):  
T.-S. Kim ◽  
J.M. Kim ◽  
C.H.D. Kwon ◽  
S.J. Kim ◽  
J.-W. Joh ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Prognostic Factors ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Poor Outcome

scholarly journals Improvement in Survival Associated With Adult-to-Adult Living Donor Liver Transplantation

2007 ◽  
Vol 133 (6) ◽  
pp. 1806-1813 ◽  
Author(s):  
Carl L. Berg ◽  
Brenda W. Gillespie ◽  
Robert M. Merion ◽  
Robert S. Brown ◽  
Michael M. Abecassis ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Improvement In Survival
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