Dual‐target inhibitors of bromodomain and extra‐terminal proteins in cancer: A review from medicinal chemistry perspectives

Medicinal Research Reviews ◽

10.1002/med.21859 ◽

2021 ◽

Author(s):

Lu Feng ◽

Guan Wang ◽

Yi Chen ◽

Gu He ◽

Bo Liu ◽

...

Keyword(s):

Medicinal Chemistry ◽

Terminal Proteins ◽

Dual Target

Privileged Scaffolds in Medicinal Chemistry

10.1039/9781782622246 ◽

2015 ◽

Cited By ~ 19

Keyword(s):

Medicinal Chemistry ◽

Privileged Scaffolds

New Synthetic Technologies in Medicinal Chemistry

10.1039/9781849733052 ◽

2011 ◽

Keyword(s):

Medicinal Chemistry

Identifying and reducing satisfaction-of-search errors: How to alleviate dual-target search costs

PsycEXTRA Dataset ◽

10.1037/e520592012-022 ◽

2010 ◽

Author(s):

Stephen R. Mitroff ◽

Kait Clark ◽

Matthew S. Cain

Keyword(s):

Search Costs ◽

Target Search ◽

Satisfaction Of Search ◽

Dual Target

Dual target search: Attention tuned to relative features, both within and across feature dimensions.

Journal of Experimental Psychology Human Perception & Performance ◽

10.1037/xhp0000851 ◽

2020 ◽

Vol 46 (11) ◽

pp. 1368-1386

Author(s):

Ashley A. York ◽

David K. Sewell ◽

Stefanie I. Becker

Keyword(s):

Target Search ◽

Dual Target

Medicinal chemistry: How arsenic stops leukaemia

Nature China ◽

10.1038/nchina.2010.62 ◽

2010 ◽

Author(s):

Felix Cheung

Keyword(s):

Medicinal Chemistry

Medicinal chemistry: Changing targets

Nature China ◽

10.1038/nchina.2010.15 ◽

2010 ◽

Author(s):

Anne Pichon

Keyword(s):

Medicinal Chemistry

Quadruplex Nucleic Acids As Targets For Medicinal Chemistry

10.1016/s0065-7743(20)x0002-9 ◽

2020 ◽

Keyword(s):

Nucleic Acids ◽

Medicinal Chemistry

Proceedings XIVth International Symposium on Medicinal Chemistry

10.1016/s0165-7208(97)x8045-6 ◽

1997 ◽

Keyword(s):

International Symposium ◽

Medicinal Chemistry

An Advance In Medicinal Chemistry

Financial Analysts Journal ◽

10.2469/faj.v8.n5.81 ◽

1952 ◽

Vol 8 (5) ◽

pp. 81-84

Author(s):

Howard A. Sumner

Keyword(s):

Medicinal Chemistry

SuFEx Activation with Ca(NTf2)2: A Unified Strategy to Access Sulfamides, Sulfamates and Sulfonamides from S(VI) Fluorides

10.26434/chemrxiv.12026811.v1 ◽

2020 ◽

Author(s):

Subham Mahapatra ◽

Cristian P. Woroch ◽

Todd W. Butler ◽

Sabrina N. Carneiro ◽

Sabrina C. Kwan ◽

...

Keyword(s):

Room Temperature ◽

Medicinal Chemistry ◽

Mild Conditions ◽

Broad Array

A method to activate sulfamoyl fluorides, fluorosulfates, and sulfonyl fluorides with calcium triflimide, and DABCO for SuFEx with amines is described. The reaction was applied to a diverse set of sulfamides, sulfamates, and sulfonamides at room temperature under mild conditions. Additionally, we highlight the application of this transformation to parallel medicinal chemistry to generate a broad array of nitrogen-based S(VI) compounds.