NMR lipid profiles of cells, tissues and body fluids. I— 1D and 2D Proton NMR of lipids from rat liver

1991 ◽  
Vol 29 (6) ◽  
pp. 594-602 ◽  
Author(s):  
Mariano Casu ◽  
Graeme J. Anderson ◽  
Gregory Choi ◽  
William A. Gibbons
1994 ◽  
Vol 35 (11) ◽  
pp. 1925-1931
Author(s):  
R K Adosraku ◽  
G T Choi ◽  
V Constantinou-Kokotos ◽  
M M Anderson ◽  
W A Gibbons

1989 ◽  
Vol 83 (3) ◽  
pp. 595-600
Author(s):  
J.D Hazle ◽  
P.A Narayana ◽  
W.A Kudrle
Keyword(s):  

1996 ◽  
Vol 320 (1) ◽  
pp. 315-319 ◽  
Author(s):  
Thomas HARI ◽  
Hans KUNZE ◽  
Ernst BOHN ◽  
Urs BRODBECK ◽  
Peter BÜTIKOFER

Glycosylphosphatidylinositol (GPI)-hydrolysing enzymes have been described in many mammalian tissues and body fluids; however, their site(s) of action and in vivo functions have remained unclear. In order to identify a possible intracellular site of GPI hydrolysis, we studied the subcellular distribution of GPI-hydrolysing activity in rat liver. We found that purified fractions from rat liver hydrolysed the GPI moieties of two GPI-anchored proteins with the specificity of a phospholipase D. This GPI-specific phospholipase D (GPI-PLD) activity was found to be highly enriched in a lysosomal fraction and showed a similar intracellular distribution to that of typical lysosomal enzymes. Our results indicate that lysosomes may represent a possible intracellular site of GPI-PLD action.


1987 ◽  
Vol 35 (10) ◽  
pp. 4332-4337 ◽  
Author(s):  
JUN OKUDA ◽  
TADAO TAGUCHI ◽  
AIKO TOMIMURA

1988 ◽  
Vol 6 (3) ◽  
pp. 300-306 ◽  
Author(s):  
J. R. Bales ◽  
J. D. Bell ◽  
J. K. Nicholson ◽  
P. J. Sadler ◽  
J. A. Timbrell ◽  
...  

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