scholarly journals Relaxation‐corrected macromolecular model enables determination of 1 H longitudinal T 1 ‐relaxation times and concentrations of human brain metabolites at 9.4T

2021 ◽  
Author(s):  
Andrew Martin Wright ◽  
Saipavitra Murali‐Manohar ◽  
Tamas Borbath ◽  
Nikolai I. Avdievich ◽  
Anke Henning
Keyword(s):  
Human Brain ◽  
Relaxation Times ◽  
Brain Metabolites

Comparison of different pulse sequences for in vivo determination of T1 relaxation times in the human brain

1988 ◽  
Vol 29 (2) ◽  
pp. 231-236 ◽  
Author(s):  
L. Kjær ◽  
O. Henriksen
Keyword(s):  
Human Brain ◽  
Pulse Sequences ◽  
Relaxation Times ◽  
T1 Relaxation

Comparison of Different Pulse Sequences for in Vivo Determination of T1 Relaxation Times in the Human Brain

1988 ◽  
Vol 29 (2) ◽  
pp. 231-236 ◽  
Author(s):  
L. Kjær ◽  
O. Henriksen
Keyword(s):  
Human Brain ◽  
Pulse Sequences ◽  
Relaxation Times ◽  
Clinical Work ◽  
Inversion Recovery ◽  
Tissue Type ◽  
Whole Body ◽  
T1 Relaxation

Quantitative in vivo determination of T1 relaxation times by magnetic resonance imaging (MRI) is hampered by several potential sources of error. This study focused on the influence of the radiofrequency pulse sequences applied with special attention to the significance of the repetition time (TR). T1 measurements were performed on the human brain using a whole body MR scanner operating at 1.5 tesla. Three different pulse sequences were compared including two 6-points inversion recovery (IR) sequences with TR = 2.0 s and 4.0, respectively, and a 12-points partial saturation inversion recovery (PSIR) sequence with TR varying between 0.24 and 8.0 s. The median T1 relaxation times obtained in cortical grey matter and cerebrospinal fluid were significantly shorter in the IR experiments at TR = 2 s than in those carried out at TR = 4 s. Concerning white matter the discrepancy was much less pronounced, but still statistically significant. Supplementary phantom measurements indicated that the higher T1 values are increasingly underestimated when TR is reduced to 2 s. The results suggest that the PSIR sequence or IR sequences with a TR > 2 × the T1 level of the tissue type investigated should be employed for accurate T1 determination by MRI in clinical work.

Comment on “Direct Determination of NMR Correlation Times from Spin−Lattice and Spin−Spin Relaxation Times”

1999 ◽  
Vol 103 (24) ◽  
pp. 4775-4776 ◽  
Author(s):  
Nicholas M. Palko ◽  
W. Robert Carper
Keyword(s):  
Spin Relaxation ◽  
Relaxation Times ◽  
Direct Determination ◽  
Correlation Times ◽  
Spin Lattice

Determination of polarization relaxation times of atomic levels

2012 ◽  
Vol 47 (5) ◽  
pp. 222-224 ◽  
Author(s):  
G. G. Adonts ◽  
E. G. Kanetsyan ◽  
M. A. Arzakantsyan
Keyword(s):  
Relaxation Times

Determination of exchange ratios in NMR and NQR spectroscopy from the 1D – relaxation dependences for the T2 – relaxation times

2017 ◽  
Vol 684 ◽  
pp. 186-190 ◽  
Author(s):  
N.Ya. Sinyavsky ◽  
N.A. Kostrikova
Keyword(s):  
Relaxation Times ◽  
T2 Relaxation

Diffusion-weighted chemical shift imaging of human brain metabolites at 7T

2014 ◽  
Vol 73 (6) ◽  
pp. 2053-2061 ◽  
Author(s):  
Ayse Ece Ercan ◽  
Aranee Techawiboonwong ◽  
Maarten J. Versluis ◽  
Andrew G. Webb ◽  
Itamar Ronen
Keyword(s):  
Chemical Shift ◽  
Human Brain ◽  
Chemical Shift Imaging ◽  
Brain Metabolites ◽  
Diffusion Weighted

Validated UPLC-MS/MS method for determination of moclobemide in human brain cell supernatant and its application to bidirectional transport study

2013 ◽  
Vol 27 (9) ◽  
pp. 1143-1149 ◽  
Author(s):  
Dai Li-Bo ◽  
Yan Miao ◽  
Li Huan-De ◽  
Fang Ping-Fei ◽  
Wang Feng ◽  
...  
Keyword(s):  
Human Brain ◽  
Brain Cell ◽  
Transport Study ◽  
Bidirectional Transport ◽  
Cell Supernatant

Determination of metal elements concentrations in human brain tissues using PIXE and EDX methods

2018 ◽  
Vol 318 (3) ◽  
pp. 2313-2319
Author(s):  
Ján Pánik ◽  
Martin Kopáni ◽  
Jakub Zeman ◽  
Miroslav Ješkovský ◽  
Jakub Kaizer ◽  
...  
Keyword(s):  
Human Brain ◽  
Metal Elements ◽  
Brain Tissues
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