Comparison of different pulse sequences for in vivo determination of T1 relaxation times in the human brain

1988 ◽  
Vol 29 (2) ◽  
pp. 231-236 ◽  
Author(s):  
L. Kjær ◽  
O. Henriksen
Keyword(s):  
Human Brain ◽  
Pulse Sequences ◽  
Relaxation Times ◽  
T1 Relaxation

Comparison of Different Pulse Sequences for in Vivo Determination of T1 Relaxation Times in the Human Brain

1988 ◽  
Vol 29 (2) ◽  
pp. 231-236 ◽  
Author(s):  
L. Kjær ◽  
O. Henriksen
Keyword(s):  
Human Brain ◽  
Pulse Sequences ◽  
Relaxation Times ◽  
Clinical Work ◽  
Inversion Recovery ◽  
Tissue Type ◽  
Whole Body ◽  
T1 Relaxation

Quantitative in vivo determination of T1 relaxation times by magnetic resonance imaging (MRI) is hampered by several potential sources of error. This study focused on the influence of the radiofrequency pulse sequences applied with special attention to the significance of the repetition time (TR). T1 measurements were performed on the human brain using a whole body MR scanner operating at 1.5 tesla. Three different pulse sequences were compared including two 6-points inversion recovery (IR) sequences with TR = 2.0 s and 4.0, respectively, and a 12-points partial saturation inversion recovery (PSIR) sequence with TR varying between 0.24 and 8.0 s. The median T1 relaxation times obtained in cortical grey matter and cerebrospinal fluid were significantly shorter in the IR experiments at TR = 2 s than in those carried out at TR = 4 s. Concerning white matter the discrepancy was much less pronounced, but still statistically significant. Supplementary phantom measurements indicated that the higher T1 values are increasingly underestimated when TR is reduced to 2 s. The results suggest that the PSIR sequence or IR sequences with a TR > 2 × the T1 level of the tissue type investigated should be employed for accurate T1 determination by MRI in clinical work.

Spin-echo methods for the determination of 31P transverse relaxation times of the ATP NMR signals in vivo

1994 ◽  
Vol 12 (1) ◽  
pp. 121-129 ◽  
Author(s):  
Klaus Straubinger ◽  
Wulf-Ingo Jung ◽  
Michael Bunse ◽  
Otto Lutz ◽  
Klaus Küper ◽  
...  
Keyword(s):  
Spin Echo ◽  
Relaxation Times ◽  
Transverse Relaxation ◽  
Nmr Signals

A proposed method for in vivo determination of lithium in human brain

1985 ◽  
Vol 30 (11) ◽  
pp. 1225-1236 ◽  
Author(s):  
D Vartsky ◽  
A LoMonte ◽  
K J Ellis ◽  
S Yasumura ◽  
S H Cohn
Keyword(s):  
Human Brain

In-vivo Determination of Relaxation Times of Musculoskeletal Relevant Tissue at 1.5 T and 3 T

2005 ◽  
Vol 177 (04) ◽  
Author(s):  
BM Wietek ◽  
J Machann ◽  
P Martirosian ◽  
C Mueller ◽  
CD Claussen ◽  
...  
Keyword(s):  
Relaxation Times

scholarly journals Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR

1999 ◽  
Vol 96 (14) ◽  
pp. 8235-8240 ◽  
Author(s):  
J. Shen ◽  
K. F. Petersen ◽  
K. L. Behar ◽  
P. Brown ◽  
T. W. Nixon ◽  
...  
Keyword(s):  
Human Brain ◽  
13C Nmr
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