Direct analysis of volatile organic compounds in human breath using a miniaturized cylindrical ion trap mass spectrometer with a membrane inlet

2002 ◽  
Vol 16 (24) ◽  
pp. 2370-2373 ◽  
Author(s):  
Leah S. Riter ◽  
Brian C. Laughlin ◽  
Eugene Nikolaev ◽  
R. Graham Cooks
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Mass Spectrometer ◽  
Ion Trap ◽  
Direct Analysis ◽  
Human Breath ◽  
Ion Trap Mass Spectrometer ◽  
Cylindrical Ion Trap ◽  
Volatile Organic

Development of an Automated Cylindrical Ion Trap Mass Spectrometer for the Determination of Atmospheric Volatile Organic Compounds

2007 ◽  
Vol 79 (13) ◽  
pp. 5040-5050 ◽  
Author(s):  
Gavin D. Edwards ◽  
P. B. Shepson ◽  
J. W. Grossenbacher ◽  
J. M. Wells ◽  
G. E. Patterson ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Mass Spectrometer ◽  
Ion Trap ◽  
Ion Trap Mass Spectrometer ◽  
Cylindrical Ion Trap ◽  
Volatile Organic

Separation of volatile organic compounds using a MEMS separation column integrated with ion trap mass spectrometer

2020 ◽  
Vol 307 ◽  
pp. 127588 ◽  
Author(s):  
Tzu-Hsuan Chang ◽  
Daniel Struk ◽  
Milad Navaei ◽  
Vladimir M. Doroshenko ◽  
Victor Laiko ◽  
...  
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Mass Spectrometer ◽  
Ion Trap ◽  
Ion Trap Mass Spectrometer ◽  
Separation Column ◽  
Volatile Organic

Ion-Trap Detection of Volatile Organic Compounds in Alveolar Breath

1992 ◽  
Vol 38 (1) ◽  
pp. 60-65 ◽  
Author(s):  
M Phillips ◽  
J Greenberg
Keyword(s):  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Molecular Sieve ◽  
Mass Spectra ◽  
Ion Trap ◽  
Normal Subjects ◽  
Human Breath ◽  
Human Volunteers ◽  
Volatile Organic ◽  
Computer Based

Abstract We describe a method for the collection and microanalysis of the volatile organic compounds in human breath. A transportable apparatus supplies subjects with purified air and samples their alveolar breath; the volatile organic compounds are captured in an adsorptive trap containing activated carbon and molecular sieve. The sample is thermally desorbed from the trap in an automated microprocessor-controlled device, concentrated by two-stage cryofocusing, and assayed by gas chromatography with ion-trap detection. Compounds are identified by reference to a computer-based library of mass spectra with subtraction of the background components present in the inspired air. We used this device to study 10 normal subjects and determined the relative abundance of the volatile organic compounds in their alveolar breath. The breath-collecting apparatus was convenient to operate and was well tolerated by human volunteers.

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