Impact of modelling intra-subject variability on tests based on non-linear mixed-effects models in cross-over pharmacokinetic trials with application to the interaction of tenofovir on atazanavir in HIV patients

Xavière Panhard; Anne-Marie Taburet; Christophe Piketti; France Mentré

doi:10.1002/sim.2622

Impact of modelling intra-subject variability on tests based on non-linear mixed-effects models in cross-over pharmacokinetic trials with application to the interaction of tenofovir on atazanavir in HIV patients

Statistics in Medicine ◽

10.1002/sim.2622 ◽

2007 ◽

Vol 26 (6) ◽

pp. 1268-1284 ◽

Cited By ~ 12

Author(s):

Xavière Panhard ◽

Anne-Marie Taburet ◽

Christophe Piketti ◽

France Mentré

Keyword(s):

Mixed Effects ◽

Mixed Effects Models ◽

Hiv Patients ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Subject Variability ◽

Non Linear

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Non-linear mixed-effects models

Chapman & Hall/CRC Handbooks of Modern Statistical Methods - Longitudinal Data Analysis ◽

10.1201/9781420011579.ch5 ◽

2008 ◽

pp. 107-141 ◽

Cited By ~ 1

Author(s):

Marie Davidian

Keyword(s):

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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Hierarchical non-linear mixed-effects models for estimating growth parameters of western Mediterranean solitary coral populations

Ecological Modelling ◽

10.1016/j.ecolmodel.2016.12.015 ◽

2017 ◽

Vol 346 ◽

pp. 1-9 ◽

Cited By ~ 1

Author(s):

Barbara Cafarelli ◽

Crescenza Calculli ◽

Daniela Cocchi ◽

Elettra Pignotti

Keyword(s):

Growth Parameters ◽

Western Mediterranean ◽

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Solitary Coral ◽

Non Linear

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Modelling HIV viral rebound using non-linear mixed effects models

Statistics in Medicine ◽

10.1002/sim.1155 ◽

2002 ◽

Vol 21 (14) ◽

pp. 2093-2108 ◽

Cited By ~ 17

Author(s):

Anthony P. Fitzgerald ◽

Victor G. DeGruttola ◽

Florin Vaida

Keyword(s):

Mixed Effects ◽

Mixed Effects Models ◽

Viral Rebound ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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Body size and growth in tropical small mammals: examining variation using non-linear mixed effects models

Journal of Zoology ◽

10.1017/s0952836905007429 ◽

2005 ◽

Vol 267 (02) ◽

pp. 211 ◽

Cited By ~ 6

Author(s):

A. D. Griffiths ◽

B. W. Brook

Keyword(s):

Body Size ◽

Small Mammals ◽

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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A sample size computation method for non-linear mixed effects models with applications to pharmacokinetics models

Statistics in Medicine ◽

10.1002/sim.1695 ◽

2004 ◽

Vol 23 (16) ◽

pp. 2551-2566 ◽

Cited By ~ 19

Author(s):

Dongwoo Kang ◽

Janice B. Schwartz ◽

Davide Verotta

Keyword(s):

Sample Size ◽

Mixed Effects ◽

Mixed Effects Models ◽

Computation Method ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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Non-linear mixed effects models for the evaluation of dissolution profiles

International Journal of Pharmaceutics ◽

10.1016/s0378-5173(02)00127-8 ◽

2002 ◽

Vol 240 (1-2) ◽

pp. 37-53 ◽

Cited By ~ 25

Author(s):

E Adams ◽

D Coomans ◽

J Smeyers-Verbeke ◽

D.L Massart

Keyword(s):

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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Fisher information matrix for non-linear mixed-effects models: evaluation and application for optimal design of enoxaparin population pharmacokinetics

Statistics in Medicine ◽

10.1002/sim.1041 ◽

2002 ◽

Vol 21 (18) ◽

pp. 2623-2639 ◽

Cited By ~ 57

Author(s):

Sylvie Retout ◽

France Mentré ◽

René Bruno

Keyword(s):

Optimal Design ◽

Population Pharmacokinetics ◽

Fisher Information ◽

Fisher Information Matrix ◽

Information Matrix ◽

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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Parameter estimation in non-linear mixed effects models with SAEM algorithm: extension from ODE to PDE

ESAIM Mathematical Modelling and Numerical Analysis ◽

10.1051/m2an/2013140 ◽

2014 ◽

Vol 48 (5) ◽

pp. 1303-1329 ◽

Cited By ~ 4

Author(s):

E. Grenier ◽

V. Louvet ◽

P. Vigneaux

Keyword(s):

Parameter Estimation ◽

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Saem Algorithm ◽

Non Linear

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Non-Linear Mixed-Effects Models with Stochastic Differential Equations: Implementation of an Estimation Algorithm

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-005-2104-x ◽

2005 ◽

Vol 32 (1) ◽

pp. 85-107 ◽

Cited By ~ 46

Author(s):

Rune V. Overgaard ◽

Niclas Jonsson ◽

Christoffer W. Tornøe ◽

Henrik Madsen

Keyword(s):

Differential Equations ◽

Stochastic Differential Equations ◽

Estimation Algorithm ◽

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Non Linear

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An improved SAEM algorithm for maximum likelihood estimation in mixtures of non linear mixed effects models

Statistics and Computing ◽

10.1007/s11222-013-9396-2 ◽

2013 ◽

Vol 24 (5) ◽

pp. 693-707 ◽

Cited By ~ 9

Author(s):

Marc Lavielle ◽

Cyprien Mbogning

Keyword(s):

Maximum Likelihood ◽

Maximum Likelihood Estimation ◽

Likelihood Estimation ◽

Mixed Effects ◽

Mixed Effects Models ◽

Linear Mixed Effects Models ◽

Linear Mixed Effects ◽

Saem Algorithm ◽

Non Linear

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