Radiosynthesis, ex vivo and in vivo evaluation of [11C]preclamol as a partial dopamine D2 agonist radioligand for positron emission tomography

Synapse ◽  
2006 ◽  
Vol 60 (4) ◽  
pp. 314-318 ◽  
Author(s):  
Neil Vasdev ◽  
Sridhar Natesan ◽  
Laurent Galineau ◽  
Armando Garcia ◽  
Winston T. Stableford ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Ex Vivo ◽  
Emission Tomography ◽  
In Vivo Evaluation ◽  
Dopamine D2 ◽  
D2 Agonist ◽  
Positron Emission ◽  
Dopamine D2 Agonist

scholarly journals In Vitro and In Vivo Evaluation of Bifunctional Bisthiosemicarbazone64Cu-Complexes for the Positron Emission Tomography Imaging of Hypoxia

2008 ◽  
Vol 51 (10) ◽  
pp. 2985-2991 ◽  
Author(s):  
Paul D. Bonnitcha ◽  
Amy L. Va̅vere ◽  
Jason S. Lewis ◽  
Jonathan R. Dilworth
Keyword(s):  
Positron Emission Tomography ◽  
Positron Emission Tomography Imaging ◽  
Emission Tomography ◽  
In Vivo Evaluation ◽  
Tomography Imaging ◽  
Positron Emission

scholarly journals Development of [11C]erlotinib Positron Emission Tomography for In Vivo Evaluation of EGF Receptor Mutational Status

2012 ◽  
Vol 19 (1) ◽  
pp. 183-193 ◽  
Author(s):  
Idris Bahce ◽  
Egbert F. Smit ◽  
Mark Lubberink ◽  
Astrid A. M. van der Veldt ◽  
Maqsood Yaqub ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Egf Receptor ◽  
Emission Tomography ◽  
In Vivo Evaluation ◽  
Mutational Status ◽  
Positron Emission

In vivo imaging of adenovirus-mediated over-expression of dopamine D2 receptors in rat striatum by positron emission tomography

Neuroreport ◽  
2000 ◽  
Vol 11 (4) ◽  
pp. 743-748 ◽  
Author(s):  
Osamu Ogawa ◽  
Hiroyuki Umegaki ◽  
Kiichi Ishiwata ◽  
Yukako Asai ◽  
Hiroyuki Ikari ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
In Vivo Imaging ◽  
D2 Receptors ◽  
Dopamine D2 Receptors ◽  
Emission Tomography ◽  
Rat Striatum ◽  
Over Expression ◽  
Dopamine D2 ◽  
Positron Emission

Synthesis, radiolabeling, in vitro and in vivo evaluation of [18F]-FPECMO as a positron emission tomography radioligand for imaging the metabotropic glutamate receptor subtype 5

2009 ◽  
Vol 36 (6) ◽  
pp. 613-622 ◽  
Author(s):  
Christophe Lucatelli ◽  
Michael Honer ◽  
Jean-Frédéric Salazar ◽  
Tobias L. Ross ◽  
P. August Schubiger ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptor ◽  
Emission Tomography ◽  
Receptor Subtype ◽  
In Vivo Evaluation ◽  
Metabotropic Glutamate ◽  
Positron Emission

scholarly journals OIn vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain

2021 ◽  
pp. 128254
Author(s):  
Sladjana Dukić-Stefanović ◽  
Thu Hang Lai ◽  
Magali Toussaint ◽  
Oliver Clauß ◽  
Ivana I. Jevtić ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Monoamine Oxidase ◽  
Emission Tomography ◽  
Monoamine Oxidase B ◽  
In Vivo Evaluation ◽  
Positron Emission ◽  
The Brain

scholarly journals In vivo evaluation of medical device-associated inflammation using a macrophage-specific positron emission tomography (PET) imaging probe

2013 ◽  
Vol 23 (7) ◽  
pp. 2044-2047 ◽  
Author(s):  
Jun Zhou ◽  
Guiyang Hao ◽  
Hong Weng ◽  
Yi-Ting Tsai ◽  
David W. Baker ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Medical Device ◽  
Pet Imaging ◽  
Emission Tomography ◽  
In Vivo Evaluation ◽  
Imaging Probe ◽  
Positron Emission

scholarly journals Use of Positron Emission Tomography to Study AT1 Receptor Regulation In Vivo

2001 ◽  
Vol 12 (7) ◽  
pp. 1350-1358
Author(s):  
ZSOLT SZABO ◽  
ROBERT C. SPETH ◽  
P. RANDY BROWN ◽  
LEVENTE KERENYI ◽  
PAN FU KAO ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Receptor Binding ◽  
Ex Vivo ◽  
Sodium Intake ◽  
Plasma Renin ◽  
Emission Tomography ◽  
Dietary Sodium ◽  
Compensatory Mechanism ◽  
Positron Emission

Abstract. Increased sodium intake and enhanced sodium sensitivity are implicated in the pathogenesis of hypertension and in the control of a major regulator of BP, the type 1 angiotensin receptor (AT1 receptor). An in vivo technique to study changes of renal AT1 receptors by dietary sodium was developed that uses positron emission tomography (PET). PET revealed that renal cortical AT1 receptor binding was increased in sodium-loaded compared with sodium-deprived dogs, which correlated with ex vivo estimations of AT1 receptor numbers. Plasma renin activity, angiotensin II, and aldosterone were inversely related to changes in AT1 receptor binding. These results demonstrate, for the first time in vivo, that the renal AT1 receptor is inversely related to the activity of the renin angiotensin system, which may provide a compensatory mechanism to prevent inappropriate fluctuations in arterial BP. The ability to measure AT1 receptor binding in vivo has potential significance for clinical studies of AT1 receptors, because PET is a noninvasive imaging technique that is readily applicable in humans.

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