Isolation, Structural, and Functional Characterization of an Apoptosis-Inducing -Amino Acid Oxidase from Leaf-Nosed Viper (Eristocophis macmahoni) Snake Venom

2000 ◽  
Vol 384 (2) ◽  
pp. 216-226 ◽  
Author(s):  
Syed Abid Ali ◽  
Stanka Stoeva ◽  
Atiya Abbasi ◽  
Junaid M. Alam ◽  
Rakez Kayed ◽  
...  
Keyword(s):  
Amino Acid ◽  
Snake Venom ◽  
Functional Characterization ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Biochemical and functional characterization of an l-amino acid oxidase isolated from Bothrops pirajai snake venom

2006 ◽  
Vol 14 (20) ◽  
pp. 7034-7043 ◽  
Author(s):  
Luiz Fernando M. Izidoro ◽  
Marcela C. Ribeiro ◽  
Guilherme R.L. Souza ◽  
Carolina D. Sant’Ana ◽  
Amelia Hamaguchi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Snake Venom ◽  
Functional Characterization ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Bothrops Pirajai

scholarly journals Isolation and biochemical, functional and structural characterization of a novel l-amino acid oxidase from Lachesis muta snake venom

Toxicon ◽  
2012 ◽  
Vol 60 (7) ◽  
pp. 1263-1276 ◽  
Author(s):  
Cristiane Bregge-Silva ◽  
Maria Cristina Nonato ◽  
Sérgio de Albuquerque ◽  
Paulo Lee Ho ◽  
Inácio L.M. Junqueira de Azevedo ◽  
...  
Keyword(s):  
Amino Acid ◽  
Snake Venom ◽  
Structural Characterization ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Lachesis Muta

Biochemical, biological and molecular characterization of an L-Amino acid oxidase (LAAO) purified from Bothrops pictus Peruvian snake venom

Toxicon ◽  
2017 ◽  
Vol 139 ◽  
pp. 74-86 ◽  
Author(s):  
Fanny Lazo ◽  
Dan E. Vivas-Ruiz ◽  
Gustavo A. Sandoval ◽  
Edith F. Rodríguez ◽  
Edgar E.G. Kozlova ◽  
...  
Keyword(s):  
Amino Acid ◽  
Molecular Characterization ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

24. Purification, biochemical and molecular characterization of an L-amino acid oxidase from Cerastes cerastes snake venom

Toxicon ◽  
2014 ◽  
Vol 91 ◽  
pp. 174
Author(s):  
Z. Abdelkafi-Koubaa ◽  
J. Jebali ◽  
M. Morjen ◽  
H. Othman ◽  
R. Zouari-Kesentini ◽  
...  
Keyword(s):  
Amino Acid ◽  
Molecular Characterization ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Isolation and pharmacological characterization of a new cytotoxic L-amino acid oxidase from Bungarus multicinctus snake venom

2018 ◽  
Vol 213 ◽  
pp. 311-320 ◽  
Author(s):  
Wuguang Lu ◽  
Lingling Hu ◽  
Jie Yang ◽  
Xiaoyan Sun ◽  
Huaijiang Yan ◽  
...  
Keyword(s):  
Amino Acid ◽  
Snake Venom ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Pharmacological Characterization

Biochemical, functional and structural characterization of Akbu-LAAO: A novel snake venom l-amino acid oxidase from Agkistrodon blomhoffii ussurensis

Biochimie ◽  
2010 ◽  
Vol 92 (4) ◽  
pp. 343-349 ◽  
Author(s):  
Ming-Zhong Sun ◽  
Chunmei Guo ◽  
Yuxiang Tian ◽  
Duo Chen ◽  
Frederick T. Greenaway ◽  
...  
Keyword(s):  
Amino Acid ◽  
Snake Venom ◽  
Structural Characterization ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Impairment of Platelet Aggregation by Echis colorata Venom Mediated by L-Amino Acid Oxidase or H2O2

1982 ◽  
Vol 48 (03) ◽  
pp. 277-282 ◽  
Author(s):  
I Nathan ◽  
A Dvilansky ◽  
T Yirmiyahu ◽  
M Aharon ◽  
A Livne
Keyword(s):  
Hydrogen Peroxide ◽  
Amino Acid ◽  
Platelet Aggregation ◽  
Snake Venom ◽  
Oxidase Activity ◽  
Enzyme Preparation ◽  
Acid Oxidase ◽  
Crude Venom ◽  
Amino Acid Oxidase ◽  
Hemostatic Disorders

SummaryEchis colorata bites cause impairment of platelet aggregation and hemostatic disorders. The mechanism by which the snake venom inhibits platelet aggregation was studied. Upon fractionation, aggregation impairment activity and L-amino acid oxidase activity were similarly separated from the crude venom, unlike other venom enzymes. Preparations of L-amino acid oxidase from E.colorata and from Crotalus adamanteus replaced effectively the crude E.colorata venom in impairment of platelet aggregation. Furthermore, different treatments known to inhibit L-amino acid oxidase reduced in parallel the oxidase activity and the impairment potency of both the venom and the enzyme preparation. H2O2 mimicked characteristically the impairment effects of L-amino acid oxidase and the venom. Catalase completely abolished the impairment effects of the enzyme and the venom. It is concluded that hydrogen peroxide formed by the venom L-amino acid oxidase plays a role in affecting platelet aggregation and thus could contribute to the extended bleeding typical to persons bitten by E.colorata.

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