Hydrogen Peroxide
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Quanying Chen ◽  
Chaoqun Ma ◽  
Shihai Yan ◽  
Jie Liang ◽  
Kai Dong ◽  

2021 ◽  
Vol 11 (1) ◽  
Mohammad Khairul Alam Sobuj ◽  
Md. Ariful Islam ◽  
Md. Shoebul Islam ◽  
Md. Mohidul Islam ◽  
Yahia Mahmud ◽  

AbstractSeaweeds are now recognized as a treasure of bioactive compounds. However, the bioactivity of seaweed originating in Bangladesh is still unexplored. So, this study was designed to explore the secondary metabolites and antioxidant activities of solvent extracts of Padina tetrastromatica and Gracilaria tenuistipitata. Phytochemical screening and FTIR spectra confirm the diverse type of bioactive compounds. Antioxidant activity of extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2, 2-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), reducing power (RP), phosphomolybdenum, hydrogen peroxide and nitric oxide (NO) scavenging assays. Here, methanolic extract of P. tetrastromatica showed highest amount of total phenolic content (85.61 mg of GA/g), total flavonoid content (41.77 mg of quercetin/g), DPPH (77.07%), ABTS (77.65%), RP (53.24 mg AAE/g), phosphomolybdenum (31.58 mg AAE/g), hydrogen peroxide (67.89%) and NO (70.64%) assays compared to its methanolic extracts of G. tenuistipitata. This study concluded that methanol as a solvent extract of brown seaweed (P. tetrastromatica) exhibited bioactivity and antioxidant potentiality which will be useful for pharmacological as well as in functional food application.

Catalysts ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1164
Qiuchen Dong ◽  
Xiangcheng Sun ◽  
Songbing He

There have been numerous studies applying iridium oxides in different applications to explore their proton-change-based reactions since the 1980s. Iridium oxide can be fabricated directly by applying electrodeposition, sputter-coating method, or oxidation of iridium wire. Generally, there have been currently two approaches in applying iridium oxide to enable its sensing applications. One was to improve or create different electrolytes with (non-)electrodeposition method for better performance of Nernst Constant with the temperature-related system. The mechanism behind the scenes were summarized herein. The other was to change the structure of iridium oxide through different kinds of templates such as photolithography patterns, or template-assisted direct growth methods, etc. to improve the sensing performance. The detection targets varied widely from intracellular cell pH, glucose in an artificial sample or actual urine sample, and the hydrogen peroxide, glutamate or organophosphate pesticides, metal-ions, etc. This review paper has focused on the mechanism of electrodeposition of iridium oxide in aqueous conditions and the sensing applications towards different biomolecules compounds. Finally, we summarize future trends on Iridium oxide based sensing and predict future work that could be further explored.

2021 ◽  
Mohammad Hayati ◽  
Seyed Mohammad Seyed Alizadeh Ganji ◽  
Seyed Hadi Shahcheraghi

Abstract The cyanidation process is the most common method applied for the extraction of gold and silver in the hydrometallurgy industry, in which, sodium cyanide is used as a leaching agent. Therefore, the wastewater of gold mines contains a wide variety of cyanide ions needing to be removed before these wastewaters can be discharged to the receiving environments. In this study, a fuzzy multi-attribute decision-making approach (Fuzzy Delphi AHP and Fuzzy TOPSIS) was used for selecting the best cyanide removal method from the wastewater of Muteh gold mine. According to the experts' opinion, three methods including calcium hypochlorite, hydrogen peroxide and sodium hypochlorite were selected as alternatives. Then, by introducing the criteria influencing decision making, including cyanide removal ability, cost of process, amount of material consumed, time, pH, ease of performance and safety, and performing separated experiments, the criteria for each of three methods were determined. Finally, sodium hypochlorite was proposed as the best method for eliminating cyanide from wastewater. It was found that the rank of methods was as sodium hypochlorite (0.517) > calcium hypochlorite (0.474) > hydrogen peroxide (0.463).

Jinqiu Liao ◽  
Li Liu ◽  
Xiaoyan Liu ◽  
Yukun Shang ◽  
Ming Yuan ◽  

Abstract In many legumes, roots that are exposed to blue light do not form nodules, and blue light induces the biosynthesis of hydrogen peroxide (H2O2). The mechanism of blue light restraining nodulation is poorly understood. Whether H2O2 induced by blue light inhibits nodulation needs to be further studied. In this work, blue light could promote the production of H2O2, activate the expression of LjRbohD and LjRbohE, while inhibit the expression of LjRbohB. After applying exogenous H2O2 and diphenyleneiodonium chloride (DPI), the results show H2O2 induced by blue light represses the nodulation of MG20. The accumulated H2O2 may be generated by LjRbohD, which supported by Q-PCR. Cryptochrome 1A, a blue light photoreceptor, is high expression under blue light. However, there seems to be no direct relationship between LjRbohD and LjCry1A. On the contrary, LjRbohB, a positive governor in the regulation of nitrogen fixation activity in L. japonicus, may be negatively regulated by LjCry1A according to the hairy roots transformation results. Therefore, the mechanisms of regulating the nodulation in L. japonicus by LjRbohB and LjRbohD are quite different under blue light. Keywords: Louts japonicus, accumulated H2O2, blue light, nodulation, LjRbohs.

2021 ◽  
Jhonatan J. Hermosillo-Nevárez ◽  
Yaneth A. Bustos-Terrones ◽  
Jesús G. Rangel-Peraza ◽  
María M. Armendáriz-Ontiveros ◽  
Leonel E. Amábilis-Sosa ◽  

2021 ◽  
Marie Paradis ◽  
Nicole Kucharowski ◽  
Gabriela Edwards ◽  
Santiago Maya Palacios ◽  
Christian Meyer ◽  

Abstract Dynamic contacts are formed between endoplasmic reticulum (ER) and mitochondria that enable the exchange of calcium and phospholipids. Disturbed contacts between ER and mitochondria impair mitochondrial dynamics and are a molecular hallmark of Parkinson’s disease. Cystein-rich with EGF-like domain (Creld) are ER-proteins associated with atrioventricular septal defects, but human CRELD1 is also a poorly characterized risk gene for Parkinson’s disease. Here we show that Creld is required for ER-mitochondria communication. Loss of Creld leads to mitochondrial hyperfusion and reduced ROS signaling in Drosophila melanogaster, Xenopus tropicalis and human cells. We found that reduced respiratory complex I activity lowers hydrogen peroxide levels, which disturbs neuronal activity and leads to impaired locomotion in Creld mutants. Our study presents a new paradigm of neuron dysfunction as a result of impaired ER-mitochondria communication and a new model for Parkinson’s disease.

2021 ◽  
Jodie A Schiffer ◽  
Stephanie V Stumbur ◽  
Maedeh Seyedolmohadesin ◽  
Yuyan Xu ◽  
William T Serkin ◽  

Hydrogen peroxide (H2O2) is the most common chemical threat that organisms face. Here, we show that H2O2 alters the bacterial food preference of Caenorhabditis elegans, enabling the nematodes to find a safe environment with food. H2O2 induces the nematodes to leave food patches of laboratory and microbiome bacteria when those bacterial communities have insufficient H2O2-degrading capacity. The nematode's behavior is directed by H2O2-sensing neurons that promote escape from H2O2 and by bacteria-sensing neurons that promote attraction to bacteria. However, the input for H2O2-sensing neurons is removed by bacterial H2O2-degrading enzymes and the bacteria-sensing neurons' perception of bacteria is prevented by H2O2. The resulting cross-attenuation provides a general mechanism that ensures the nematode's behavior is faithful to the lethal threat of hydrogen peroxide, increasing the nematode's chances of finding a niche that provides both food and protection from hydrogen peroxide.

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