Bayesian Inference in Physiologically-based Pharmacokinetic Modeling: Application to Aniticancer Drug Development

State-of-the-Art Review on Physiologically Based Pharmacokinetic Modeling in Pediatric Drug Development

Clinical Pharmacokinetics ◽

10.1007/s40262-018-0677-y ◽

2018 ◽

Vol 58 (1) ◽

pp. 1-13 ◽

Cited By ~ 19

Author(s):

Venkata Yellepeddi ◽

Joseph Rower ◽

Xiaoxi Liu ◽

Shaun Kumar ◽

Jahidur Rashid ◽

...

Keyword(s):

Drug Development ◽

State Of The Art ◽

Pediatric Drug ◽

A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12678 ◽

2021 ◽

Author(s):

Trevor N. Johnson ◽

Ben G. Small ◽

Eva Gil Berglund ◽

Karen Rowland Yeo

Keyword(s):

Drug Development ◽

Best Practice ◽

Pediatric Drug ◽

Physiologically Based ◽

Practice Framework

Physiologically based pharmacokinetic modeling as a tool for drug development

Journal of Pharmacokinetics and Biopharmaceutics ◽

10.1007/bf02354273 ◽

1995 ◽

Vol 23 (2) ◽

pp. 217-229 ◽

Cited By ~ 43

Author(s):

Steven B. Charnick ◽

Ryosei Kawai ◽

Jerry R. Nedelman ◽

Michel Lemaire ◽

Werner Niederberger ◽

...

Keyword(s):

Drug Development ◽

Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2014.45 ◽

2014 ◽

Vol 3 (11) ◽

pp. 1-13 ◽

Cited By ~ 77

Author(s):

A R Maharaj ◽

A N Edginton

Keyword(s):

Drug Development ◽

Modeling And Simulation ◽

Pediatric Drug ◽

Pharmacokinetic Modeling And Simulation

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling in Pediatric Drug Development: A Clinician’s Request for a More Integrated Approach

Journal of Biomedicine and Biotechnology ◽

10.1155/2012/103763 ◽

2012 ◽

Vol 2012 ◽

pp. 1-3 ◽

Cited By ~ 10

Author(s):

Karel Allegaert ◽

Anne Smits ◽

Johannes N. van den Anker

Keyword(s):

Drug Development ◽

Integrated Approach ◽

Pediatric Drug ◽

Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12110 ◽

2016 ◽

Vol 5 (10) ◽

pp. 505-515 ◽

Cited By ~ 7

Author(s):

IE Templeton ◽

Y Chen ◽

J Mao ◽

J Lin ◽

H Yu ◽

...

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling and Allometric Scaling in Pediatric Drug Development: Where Do We Draw the Line?

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1834 ◽

2021 ◽

Vol 61 (S1) ◽

Author(s):

Trevor N. Johnson ◽

Alice B. Ke

Keyword(s):

Drug Development ◽

Allometric Scaling ◽

Pediatric Drug ◽

Physiologically Based Pharmacokinetic Modeling in Pediatric Oncology Drug Development

Drug Metabolism and Disposition ◽

10.1124/dmd.115.068031 ◽

2016 ◽

Vol 44 (7) ◽

pp. 934-943 ◽

Cited By ~ 17

Author(s):

N. Rioux ◽

N. J. Waters

Keyword(s):

Drug Development ◽

Pediatric Oncology ◽

Oncology Drug ◽

Physiologically Based ◽

Oncology Drug Development

Commentary on “physiologically based pharmacokinetic modeling as a tool for drug development”

Journal of Pharmacokinetics and Biopharmaceutics ◽

10.1007/bf02354274 ◽

1995 ◽

Vol 23 (2) ◽

pp. 231-235 ◽

Cited By ~ 7

Author(s):

Thomas M. Ludden ◽

William R. Gillespie ◽

William J. Bachman

Keyword(s):

Drug Development ◽

Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1489 ◽

2019 ◽

Vol 59 (S1) ◽

Cited By ~ 3

Author(s):

Kit Wun Kathy Cheung ◽

Bianca D. Groen ◽

Gilbert J. Burckart ◽

Lei Zhang ◽

Saskia N. Wildt ◽

...

Keyword(s):

Drug Development ◽

Membrane Transporters ◽

Developmental Changes ◽

Pediatric Drug ◽