Physiologically Based Pharmacokinetic Modeling and Simulation in Pediatric Drug Development

Pediatric Drug ◽

Physiologically Based ◽

State-of-the-Art Review on Physiologically Based Pharmacokinetic Modeling in Pediatric Drug Development

Clinical Pharmacokinetics ◽

10.1007/s40262-018-0677-y ◽

2018 ◽

Vol 58 (1) ◽

pp. 1-13 ◽

Cited By ~ 19

Author(s):

Venkata Yellepeddi ◽

Joseph Rower ◽

Xiaoxi Liu ◽

Shaun Kumar ◽

Jahidur Rashid ◽

...

Keyword(s):

Drug Development ◽

State Of The Art ◽

Pediatric Drug ◽

A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12678 ◽

2021 ◽

Author(s):

Trevor N. Johnson ◽

Ben G. Small ◽

Eva Gil Berglund ◽

Karen Rowland Yeo

Keyword(s):

Drug Development ◽

Best Practice ◽

Pediatric Drug ◽

Physiologically Based ◽

Practice Framework

Physiologically Based Pharmacokinetic Modeling in Pediatric Drug Development: A Clinician’s Request for a More Integrated Approach

Journal of Biomedicine and Biotechnology ◽

10.1155/2012/103763 ◽

2012 ◽

Vol 2012 ◽

pp. 1-3 ◽

Cited By ~ 10

Author(s):

Karel Allegaert ◽

Anne Smits ◽

Johannes N. van den Anker

Keyword(s):

Drug Development ◽

Integrated Approach ◽

Pediatric Drug ◽

Physiologically Based Pharmacokinetic Modeling and Allometric Scaling in Pediatric Drug Development: Where Do We Draw the Line?

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1834 ◽

2021 ◽

Vol 61 (S1) ◽

Author(s):

Trevor N. Johnson ◽

Alice B. Ke

Keyword(s):

Drug Development ◽

Allometric Scaling ◽

Pediatric Drug ◽

Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1489 ◽

2019 ◽

Vol 59 (S1) ◽

Cited By ~ 3

Author(s):

Kit Wun Kathy Cheung ◽

Bianca D. Groen ◽

Gilbert J. Burckart ◽

Lei Zhang ◽

Saskia N. Wildt ◽

...

Keyword(s):

Drug Development ◽

Membrane Transporters ◽

Developmental Changes ◽

Pediatric Drug ◽

Impact of Physiologically Based Pharmacokinetic Modeling and Simulation in Drug Development

Drug Metabolism and Disposition ◽

10.1124/dmd.113.052803 ◽

2013 ◽

Vol 41 (12) ◽

pp. 1994-2003 ◽

Cited By ~ 27

Author(s):

Carole E. Shardlow ◽

Grant T. Generaux ◽

Aarti H. Patel ◽

Guoying Tai ◽

Thuy Tran ◽

...

Keyword(s):

Drug Development ◽

Modeling And Simulation ◽

Physiologically Based ◽

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano ◽

10.1021/acsnano.9b08142 ◽

2020 ◽

Vol 14 (3) ◽

pp. 3075-3095 ◽

Cited By ~ 16

Author(s):

Yi-Hsien Cheng ◽

Chunla He ◽

Jim E. Riviere ◽

Nancy A. Monteiro-Riviere ◽

Zhoumeng Lin

Keyword(s):

Modeling And Simulation ◽

Meta Analysis ◽

Simulation Approach ◽

Nanoparticle Delivery ◽

Physiologically Based ◽

Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

The Journal of Clinical Pharmacology ◽

10.1177/0091270011415528 ◽

2012 ◽

Vol 52 (S1) ◽

Cited By ~ 69

Author(s):

Ping Zhao ◽

Manuela de L. T. Vieira ◽

Joseph A. Grillo ◽

Pengfei Song ◽

Ta‐Chen Wu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Modeling And Simulation ◽

Physiologically Based ◽

Best Practice in the Use of Physiologically Based Pharmacokinetic Modeling and Simulation to Address Clinical Pharmacology Regulatory Questions

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2012.68 ◽

2012 ◽

Vol 92 (1) ◽

pp. 17-20 ◽

Cited By ~ 127

Author(s):

P Zhao ◽

M Rowland ◽

S-M Huang

Keyword(s):

Clinical Pharmacology ◽

Modeling And Simulation ◽

Best Practice ◽

Physiologically Based ◽

Assessing drug interaction risk of the grapefruit juice component and dietary supplement 6′,7′‐dihydroxybergamottin via physiologically‐based pharmacokinetic modeling and simulation

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.1103.4 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Garrett Robert Ainslie ◽

Brandon T Gufford ◽

Christina S Won ◽

Kristina K Wolf ◽

Mary F Paine

Keyword(s):

Drug Interaction ◽

Modeling And Simulation ◽

Dietary Supplement ◽

Grapefruit Juice ◽

Physiologically Based ◽