Secondary and Primary Amine Catalysts for Iminium Catalysis

2009 ◽  
pp. 281-347 ◽  
Author(s):  
John B. Brazier ◽  
Nicholas C. O. Tomkinson
Keyword(s):  
Primary Amine ◽  
Amine Catalysts

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleo-philes to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

Another Stereochemical Model for Cinchona-Derived Primary Amine Catalysts

Synfacts ◽  
2013 ◽  
Vol 9 (08) ◽  
pp. 0891-0891
Keyword(s):  
Primary Amine ◽  
Amine Catalysts

Highly Enantioselective Directsyn- andanti-Aldol Reactions of Dihydroxyacetones Catalyzed by Chiral Primary Amine Catalysts

2008 ◽  
Vol 10 (4) ◽  
pp. 653-656 ◽  
Author(s):  
Sanzhong Luo ◽  
Hui Xu ◽  
Long Zhang ◽  
Jiuyuan Li ◽  
Jin-Pei Cheng
Keyword(s):  
Primary Amine ◽  
Aldol Reactions ◽  
Amine Catalysts

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleophiles to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

Secondary and Primary Amine Catalysts for Iminium Catalysis

2009 ◽  
pp. 281-347 ◽  
Author(s):  
John B. Brazier ◽  
Nicholas C. O. Tomkinson
Keyword(s):  
Primary Amine ◽  
Amine Catalysts

Asymmetric Synthesis of Tetrahydroquinolinesvia1,5-Hydride Transfer/Cyclization Catalyzed by Chiral Primary Amine Catalysts

2013 ◽  
Vol 355 (16) ◽  
pp. 3131-3136 ◽  
Author(s):  
Young Ku Kang ◽  
Dae Young Kim
Keyword(s):  
Asymmetric Synthesis ◽  
Primary Amine ◽  
Hydride Transfer ◽  
Amine Catalysts

Asymmetric Double Michael Reaction Catalyzed by Simple Primary Amine Catalysts: A Straightforward Approach to Construct Spirocyclic Oxindoles

2012 ◽  
Vol 30 (5) ◽  
pp. 1185-1188 ◽  
Author(s):  
Xiya Luo ◽  
Liangliang Wang ◽  
Lin Peng ◽  
Jianfei Bai ◽  
Lina Jia ◽  
...  
Keyword(s):  
Primary Amine ◽  
Michael Reaction ◽  
Straightforward Approach ◽  
Amine Catalysts

Biphasic synthesis of colloidal mesoporous silica nanoparticles using primary amine catalysts

2012 ◽  
Vol 385 (1) ◽  
pp. 41-47 ◽  
Author(s):  
Junzheng Wang ◽  
Ayae Sugawara-Narutaki ◽  
Atsushi Shimojima ◽  
Tatsuya Okubo
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Primary Amine ◽  
Mesoporous Silica Nanoparticles ◽  
Amine Catalysts

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleophiles to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

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