Mesangiocapillary glomerulonephritis

Author(s):  
P. W. Mathieson
1993 ◽  
Vol 8 (8) ◽  
pp. 783-784 ◽  
Author(s):  
B. Rincon ◽  
C. Bernis ◽  
A arcia ◽  
J. A Traver

1993 ◽  
Vol 43 (2) ◽  
pp. 381-386 ◽  
Author(s):  
Masuji Hattori ◽  
Youngki Kim ◽  
Michael W. Steffes ◽  
S. Michael Mauer

Author(s):  
Mark Oette ◽  
Marvin J. Stone ◽  
Hendrik P. N. Scholl ◽  
Peter Charbel Issa ◽  
Monika Fleckenstein ◽  
...  

Nephron ◽  
1984 ◽  
Vol 38 (3) ◽  
pp. 145-153 ◽  
Author(s):  
D. Zamurovic ◽  
J. Churg

Nephron ◽  
1985 ◽  
Vol 40 (4) ◽  
pp. 385-390 ◽  
Author(s):  
E. McGinley ◽  
R. Watkins ◽  
A. McLay ◽  
J.M. Boulton-Jones

Nephron ◽  
1995 ◽  
Vol 69 (2) ◽  
pp. 178-179 ◽  
Author(s):  
E.F.H. van Bommel ◽  
A.J. Ouwehand ◽  
A.H. Mulder ◽  
W. Weimar

1990 ◽  
Vol 27 (1) ◽  
pp. 26-34 ◽  
Author(s):  
P. F. Frelier ◽  
D. L. Armstrong ◽  
J. Pritchard

Morphologic examination of four Finnish Landrace mixed-breed lambs, 27 to 35 days of age, affected with mesangiocapillary glomerulonephritis type 1, demonstrated a progressive glomerulonephritis. By 27 days of age, three lambs had crescents in 58 to 93% of glomeruli. These three lambs were also uremic. The accelerated rate of crescent formation was attributed to infiltrating polymorphonuclear leukocytes and monocytes, the result of discontinuities (gaps) in the glomerular basement membrane, and to the loss of the integrity of Bowman's capsule. In the three lambs, platelets were identified adjacent to the endothelium or denuded glomerular basement membrane. Two distinctly different types of crescents were noted, apparently dependent on the integrity of Bowman's capsule. One type resulted from the influx of inflammatory cells and dissociation of parietal epithelial cells from Bowman's capsule. The other type was more extensive and contained collagen and was associated with damage to Bowman's capsule resulting in cellular infiltration from the interstitium and sclerosis. Based on morphologic similarities, ovine mesangiocapillary glomerulonephritis is a suitable model for studying the pathogenesis and treatment of mesangiocapillary glomerulonephritis type 1 in human beings.


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