Medium Recycling as an Operational Strategy to Increase Plant Secondary Metabolite Formation

1999 ◽  
pp. 157-163 ◽  
Author(s):  
Minoru Seki ◽  
Shintaro Furusaki
Keyword(s):  
Secondary Metabolite ◽  
Plant Secondary Metabolite ◽  
Metabolite Formation ◽  
Operational Strategy ◽  
Medium Recycling

scholarly journals Inhibition of Acetylcholinesterase and Butyrylcholinesterase by a Plant Secondary Metabolite Boldine

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Adam Kostelnik ◽  
Miroslav Pohanka
Keyword(s):  
Toxic Effect ◽  
Secondary Metabolite ◽  
Cholinesterase Inhibitor ◽  
In Silico ◽  
Chemical Compounds ◽  
Spectrophotometric Assay ◽  
Plant Secondary Metabolite ◽  
Mechanism Of Inhibition ◽  
In Silico Study ◽  
Natural Alkaloid

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are two enzymes sensitive to various chemical compounds having ability to bind to crucial parts of these enzymes. Boldine is a natural alkaloid and it was mentioned in some older works that it can inhibit some kinds of AChE. We reinvestigated this effect on AChE and also on BChE using acetyl (butyryl) thiocholine and Ellman’s reagents as standard substances for spectrophotometric assay. We found out IC50 of AChE equal to 372 μmol/l and a similar level to BChE, 321 μmol/l. We conclude our experiment by a finding that boldine is cholinesterase inhibitor; however we report significantly weaker inhibition than that suggested in literature. Likewise, we tried to investigate the mechanism of inhibition and completed it with in silico study. Potential toxic effect on cholinesterases in real conditions is also discussed.

Plant secondary metabolite polymorphisms and the extended chemical phenotype

2012 ◽  
pp. 247-268 ◽  
Author(s):  
Glenn R. Iason ◽  
Ben D. Moore ◽  
Jack J. Lennon ◽  
Jenni A. Stockan ◽  
Graham H. R. Osler ◽  
...  
Keyword(s):  
Secondary Metabolite ◽  
Plant Secondary Metabolite

Nutritional Costs of a Plant Secondary Metabolite Explain Selective Foraging by Ruffed Grouse

Ecology ◽  
1996 ◽  
Vol 77 (4) ◽  
pp. 1103-1115 ◽  
Author(s):  
Christopher G. Guglielmo ◽  
William H. Karasov ◽  
Walter J. Jakubas
Keyword(s):  
Secondary Metabolite ◽  
Plant Secondary Metabolite ◽  
Ruffed Grouse ◽  
Selective Foraging
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