Evidence for Conformational Changes in Concanavalin A Upon Binding of Saccharides as Determined from Solvent Water Proton Magnetic Relaxation Rate Dispersion Measurements

Author(s):  
R. D. Brown ◽  
C. F. Brewer ◽  
S. H. Koenig ◽  
Brian H. Barber ◽  
A. Dean Sherry ◽  
...  
1978 ◽  
Vol 65 (3) ◽  
pp. 592-594 ◽  
Author(s):  
D.D Eley ◽  
M.J Hey ◽  
C.K Rix

1992 ◽  
Vol 38 (12) ◽  
pp. 2401-2404 ◽  
Author(s):  
S Aime ◽  
W Dastrú ◽  
M Fasano ◽  
A Arnelli ◽  
M Castagnola ◽  
...  

Abstract We report a new method for the quantitative determination of human methemoglobin (metHb) based on the measurement of the solvent-water proton-nuclear magnetic resonance (NMR) relaxation rate R1 [normalized to 1 mmol/L hemoglobin (Hb) concentration]. MetHb (%) is estimated from the linear dependence of R1 on the metHb concentration, taking into account the simple relationship [MetHb] = [(R1 - R1HbO2)/(R1metHb - R1HbO2)].100, where R1HbO2 and R1metHb are values for the solvent-water relaxation rate of standard 1.0 mmol/L solutions of the oxygenated derivative of human hemoglobin (HbO2) and of metHb, respectively. The minimum metHb that may be determined from the analysis of the experimental data is 0.5 +/- 0.4%.


1974 ◽  
Vol 351 (2) ◽  
pp. 230-236 ◽  
Author(s):  
Mario Terenzi ◽  
Adelio Rigo ◽  
Cafiero Franconi ◽  
Bruno Mondovì ◽  
Lilia Calabrese ◽  
...  

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