Sprouting of Mossy Fibers in the Hippocampus of Epileptic Human and Rat

Author(s):  
Alfonso Represa ◽  
Evelyne Tremblay ◽  
Yehezkel Ben-Ari
Keyword(s):  
Hippocampus ◽  
2021 ◽  
Author(s):  
Brandy A. Briones ◽  
Thomas J. Pisano ◽  
Miah N. Pitcher ◽  
Amanda E. Haye ◽  
Emma J. Diethorn ◽  
...  

2000 ◽  
Vol 39 (12) ◽  
pp. 2288-2301 ◽  
Author(s):  
Nicola Berretta ◽  
Aleksej V Rossokhin ◽  
Alexander M Kasyanov ◽  
Maxim V Sokolov ◽  
Enrico Cherubini ◽  
...  

2008 ◽  
Vol 445 (1) ◽  
pp. 62-67 ◽  
Author(s):  
Andrea Gómez-Palacio-Schjetnan ◽  
Martha L. Escobar

Hippocampus ◽  
1993 ◽  
Vol 3 (3) ◽  
pp. 257-268 ◽  
Author(s):  
Alfonso Represa ◽  
Isabel Jorquera ◽  
Gildas le gal la Salle ◽  
Yehezkel Ben-Ari

2006 ◽  
Vol 24 (8) ◽  
pp. 486-486
Author(s):  
H. Fujisawa ◽  
F. Suto ◽  
T. Yagi ◽  
A. Chédotal ◽  
K.J. Mitchell
Keyword(s):  

eLife ◽  
2018 ◽  
Vol 7 ◽  
Author(s):  
Andrei Khilkevich ◽  
Juan Zambrano ◽  
Molly-Marie Richards ◽  
Michael Dean Mauk

Most movements are not unitary, but are comprised of sequences. Although patients with cerebellar pathology display severe deficits in the execution and learning of sequences (Doyon et al., 1997; Shin and Ivry, 2003), most of our understanding of cerebellar mechanisms has come from analyses of single component movements. Eyelid conditioning is a cerebellar-mediated behavior that provides the ability to control and restrict inputs to the cerebellum through stimulation of mossy fibers. We utilized this advantage to test directly how the cerebellum can learn a sequence of inter-connected movement components in rabbits. We show that the feedback signals from one component are sufficient to serve as a cue for the next component in the sequence. In vivo recordings from Purkinje cells demonstrated that all components of the sequence were encoded similarly by cerebellar cortex. These results provide a simple yet general framework for how the cerebellum can use simple associate learning processes to chain together a sequence of appropriately timed responses.


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