Cerebral Small Vessel Disease, Hypertension, and Cognitive Function

2010 ◽  
pp. 211-224
Author(s):  
Elizabeth K. Geary ◽  
David L. Nyenhuis
Keyword(s):  
Cognitive Function ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Vessel Disease

Does cerebral small vessel disease predict future decline of cognitive function in elderly people with type 2 diabetes?

2011 ◽  
Vol 94 (1) ◽  
pp. 91-99 ◽  
Author(s):  
Rui Imamine ◽  
Takahiko Kawamura ◽  
Toshitaka Umemura ◽  
Hiroyuki Umegaki ◽  
Naoko Kawano ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cognitive Function ◽  
Elderly People ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Vessel Disease

Basal Ganglia Enlarged Perivascular Spaces are Linked to Cognitive Function in Patients with Cerebral Small Vessel Disease

2014 ◽  
Vol 11 (2) ◽  
pp. 136-141 ◽  
Author(s):  
Marjolein Huijts ◽  
Annelien Duits ◽  
Julie Staals ◽  
Abraham Kroon ◽  
Peter Leeuw ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Basal Ganglia ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Perivascular Spaces ◽  
Vessel Disease

scholarly journals Diffusion tensor tractography in cerebral small vessel disease: correlation with cognitive function

2017 ◽  
Vol 31 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Maria M D’Souza ◽  
SP Gorthi ◽  
Kunal Vadwala ◽  
Richa Trivedi ◽  
C Vijayakumar ◽  
...  
Keyword(s):  
Cognitive Function ◽  
White Matter ◽  
Diffusion Tensor ◽  
Small Vessel Disease ◽  
Surrogate Marker ◽  
Mean Diffusivity ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
White Matter Damage ◽  
Vessel Disease

Background Patients with cerebral small vessel disease may suffer from varying levels of cognitive deficit and may progress on to vascular dementia. The extent of involvement, as seen on conventional magnetic resonance (MR) measures, correlates poorly with the level of cognitive decline. The purpose of this study was to investigate the utility of diffusion tensor imaging (DTI) as a marker for white matter damage in small vessel disease and to assess its correlation with cognitive function. Methods Thirty consecutive patients with cerebral small vessel disease underwent conventional MR imaging, DTI, and neuropsychological assessment. Results On tractographic analysis, fractional anisotropy was significantly reduced while mean diffusivity significantly increased in several white matter tracts. The alteration in DTI indices correlated well with cognitive function. No significant correlation was identified between T2 lesion load and cognitive performance. Conclusions Tractographic analysis of white matter integrity is a useful measure of disease severity and correlates well with cognitive function. It may have a significant potential in monitoring disease progression and may serve as a surrogate marker for treatment trials.

Effect of cerebral small vessel disease on cognitive function and TLR4 expression in hippocampus

2019 ◽  
Vol 67 ◽  
pp. 210-214
Author(s):  
Yamin Zhang ◽  
Yi Zhang ◽  
Ruipeng Wu ◽  
Fulin Gao ◽  
Peixi Zang ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Tlr4 Expression ◽  
Vessel Disease
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