AbstractFood security is a major public health priority in Cameroon, amidst climate change and sea level rise (CC/SLR), vis-à-vis the ever-increasing population growth with associated challenges. CC/SLR, singly or combine, is well known to have severe impacts on agricultural productivity, food security, socioeconomic activities and ecosystem (environment, plant and animal) health systems in coastal areas. They contribute to natural disasters including erosion, flooding, inundation of coastal lowlands, and saltwater intrusion, altogether reducing agricultural productivity. Additionally, these disasters provoke adverse animal, human, and environmental health implications; reduction in tourism; and potential close of some socioeconomic activities that constitute secondary (after agriculture), or main source of livelihood/income for many coastal indigents. Although there are inadequate reports on the impacts of CC/SLR, preliminary reports point to negative effects on crop production and socioeconomic activities in coastal Cameroon. This chapter highlights the susceptibility of coastal Cameroon agriculture and socioeconomic activities to CC/SLR. Furthermore, it has propose agricultural (CC/SLR and non-climatic) and educational intervention socioeconomic strategies for the mitigation and adaptation to CC/SLR and for sustainable agricultural productivity in coastal Cameroon. The proposed strategies may provide a small contribution toward a wider multi-stakeholder pool of strategies and which, when applied, may enhance food security in coastal Cameroon amidst CC/SLR and promote socioeconomic and touristic activities while reducing negative implications on animal, plant, human, and environmental health.