Perioperative Analgesia by Opioids: Rationale and Practical Basics

2014 ◽  
pp. 85-91
Author(s):  
S. Robard
2018 ◽  
Vol 5 (2) ◽  
pp. 28-33
Author(s):  
Atasi Das ◽  
◽  
Amit Kumar Bandyopadhyay ◽  
Sudipta Kumar Mandal ◽  
Juthika Biswas ◽  
...  

Author(s):  
Panayotis XIROMERITIS ◽  
Ioannis KALOGIANNIDIS ◽  
Efthymios PAPADOPOULOS ◽  
Nikos PRAPAS ◽  
Yannis PRAPAS

2021 ◽  
pp. rapm-2020-102352
Author(s):  
Sarah A Bachman ◽  
Johan Lundberg ◽  
Michael Herrick

Thoracic epidural analgesia (TEA) is an established gold standard for postoperative pain control especially following laparotomy and thoracotomy. The safety and efficacy of TEA is well known when the attention to patient selection is upheld. Recently, the use of fascial plane blocks (FPBs) has evolved as an alternative to TEA most likely because these blocks avoid problems such as neurological comorbidity, coagulation disorders, epidural catheter failure and hypotension due to sympathetic denervation. However, if an FPB is performed, postoperative monitoring and adjuvant treatments are still necessary. Also, the true efficacy of FPBs is questioned. Thus, should we prioritize less efficient analgesic regimens with FPBs when preventive treatment strategies for epidural catheter failure and hypotension exist for TEA? It is time to promote and underscore the benefits of TEA provided to patients undergoing major open surgical procedures. In our mind, FPBs and landmark-guided techniques should be limited to less extensive surgery and when either neuraxial blockade is contraindicated or resources for optimal epidural catheter placement and maintenance are not available.


2021 ◽  
pp. 030089162110200
Author(s):  
Giulio Luca Rosboch ◽  
Edoardo Ceraolo ◽  
Ilaria De Domenici ◽  
Francesco Guerrera ◽  
Eleonora Balzani ◽  
...  

Objective: The choice of analgesia after cancer surgery may play a role in the onset of cancer recurrence. Particularly opioids seem to promote cancer cell proliferation and migration. Based on this consideration, we assessed the impact of perioperative analgesia choice on cancer recurrence after curative surgery for stage I non-small cell lung cancer (NSCLC). Methods: We retrospectively reviewed the records of all patients undergoing lung resection for stage I NSCLC between January 2005 and December 2012. Patients received analgesia either by peridural (PERI group) or intravenous analgesia with opioids (EV group). Follow-up was concluded in August 2019. Five-year cumulative incidence of recurrence and overall survival were evaluated and adjusted using a propensity score matching method. Results: A total of 382 patients were evaluated, 312 belonging to the PERI group (81.7%) and 70 to the EV group (18.3%). There was no statistically significant difference between the two groups in 5-year cumulative incidence of recurrence ( p = 0.679) or overall survival rates ( p = 0.767). These results were confirmed after adjustment for propensity score matching for cumulative incidence of recurrence ( p = 0.925) or overall survival ( p = 0.663). Conclusions: We found no evidence suggesting an association between perioperative analgesia choice and recurrence-free survival or overall survival in patients undergoing surgical resection of stage I NSCLC.


2021 ◽  
Vol 73 ◽  
pp. 110383
Author(s):  
Tuhin Mistry ◽  
Aishwarya Madhav Bhat ◽  
Jagannathan Balavenkatasubramanian ◽  
Madhanmohan Chandramohan ◽  
Kartik Sonawane

1990 ◽  
Vol 4 (3) ◽  
pp. 368-383 ◽  
Author(s):  
David L. Brown ◽  
Randall L. Carpenter

Sign in / Sign up

Export Citation Format

Share Document