Natural History and Pathophysiology of Functional Ischaemic Mitral Regurgitation

Author(s):  
K. M. John Chan
1996 ◽  
Vol 27 (2) ◽  
pp. 296
Author(s):  
Lieng H. Ling ◽  
Maurice E. Sarano ◽  
A.Jamil Tajik ◽  
James B. Seward

2013 ◽  
Vol 61 (10) ◽  
pp. E433
Author(s):  
Diana Magee ◽  
Devin Chetan ◽  
Yasuhiro Kotani ◽  
Jae-Sung Son ◽  
Mark Friedberg ◽  
...  

1991 ◽  
Vol 12 (suppl B) ◽  
pp. 5-9 ◽  
Author(s):  
J. P. Delahaye ◽  
J. P. Gare ◽  
E. Viguier ◽  
F. Delahaye ◽  
G. De Gevigney ◽  
...  

2017 ◽  
Vol 2017 (1) ◽  
Author(s):  
Andrew D Maslow ◽  
Athena Poppas

Mitral regurgitation is the second most common valvular disorder requiring surgical intervention worldwide. This review summarizes the current understanding of primary, degenerative mitral regurgitation with respect to etiology, comprehensive assessment, natural history and management. The new concept of staging of the valvular disorders, newer predictors of adverse and controversy of ‘‘watchful waiting’’ versus ‘‘early surgical intervention’’ for severe, asymptomatic, primary mitral regurgitation are addressed. 


Author(s):  
Md Faisal Talukder

Degenerative Mitral Valve Disease (DMVD) is common in developed countries that frequently causes mitral regurgitation (MR). The natural history of DMVD is not well demonstrated. Therefore, timely and suitable interventions are the determinant of post-intervention clinical outcomes, life quality, and life expectancy of patients. The severity of MR can be precisely assessed by doppler-echocardiographic imaging. However, no medical management has been proven to be effective in averting the volume overload related sequel of asymptomatic degenerative MR. Therefore, mitral valve surgery (MVS) is the gold standard treatment strategy for DMVD. Notwithstanding, MVS is the only sorts of treatment strategy which provides long term natural and complication-free clinical outcome to otherwise healthy DMVD patients. However, mitral valve (MV) repair provides better clinical outcomes compared to MV replacement, along with the significant reduction of postoperative mortality rate about 70%. Currently, MVS is carried out using minimally invasive techniques or robotic-assisted techniques. Nonetheless, MVS using percutaneous techniques is evolving in the treatment for DMVD patients. This state-of-the-art-review is aimed to delineate the recent knowledge of DMVD, which includes the natural history of the disease, diagnostic modalities, recent treatment strategies, and clinical follow-up results.


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