Meta-Analyses of Clinical Trials Versus Diagnostic Test Accuracy Studies

2018 ◽  
pp. 31-40
Author(s):  
Michail Tsagris ◽  
Konstantinos C. Fragkos
Keyword(s):  
Clinical Trials ◽  
Diagnostic Test ◽  
Diagnostic Test Accuracy ◽  
Test Accuracy ◽  
Meta Analyses

Meta-analyses of diagnostic test accuracy could not be reproduced

2020 ◽  
Vol 127 ◽  
pp. 161-166
Author(s):  
Inge Stegeman ◽  
Mariska M.G. Leeflang
Keyword(s):  
Diagnostic Test ◽  
Diagnostic Test Accuracy ◽  
Test Accuracy ◽  
Meta Analyses

scholarly journals Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy: The PRISMA-DTA Statement

Radiology ◽  
2018 ◽  
Vol 289 (2) ◽  
pp. 313-314 ◽  
Author(s):  
Robert A. Frank ◽  
Patrick M. Bossuyt ◽  
Matthew D. F. McInnes
Keyword(s):  
Diagnostic Test ◽  
Systematic Reviews ◽  
Diagnostic Test Accuracy ◽  
Test Accuracy ◽  
Meta Analyses

scholarly journals Small-study effects and time trends in diagnostic test accuracy meta-analyses: a meta-epidemiological study

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Wynanda Annefloor van Enst ◽  
Christiana A Naaktgeboren ◽  
Eleanor A Ochodo ◽  
Joris AH de Groot ◽  
Mariska M Leeflang ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Diagnostic Test ◽  
Time Trends ◽  
Diagnostic Test Accuracy ◽  
Small Study ◽  
Test Accuracy ◽  
Meta Analyses

scholarly journals Protocol for a systematic review of the diagnostic test accuracy of tests for IgE-mediated food allergy

2021 ◽  
Author(s):  
Jon Genuneit ◽  
Sashini Jayasinghe ◽  
CARMEN RIGGIONI ◽  
Rachel Peters ◽  
Derek Chu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Food Allergy ◽  
Diagnostic Test ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Diagnostic Test Accuracy ◽  
Test Accuracy ◽  
Index Test ◽  
Ige Mediated ◽  
Meta Analyses

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of updating the guidelines on the diagnosis and management of food allergy. The existing guidelines are based on a systematic review of the literature until 30th September 2012. Therefore, a new systematic review must be undertaken to inform the new guidelines. This systematic review aims to assess the accuracy of index tests to support the diagnosis of IgE-mediated food allergy. Methods: The databases Cochrane CENTRAL (Trials), MEDLINE (OVID) and Embase (OVID) will be searched for diagnostic test accuracy studies from 1st October 2012 to 30th June 2021. Inclusion and exclusion criteria will be used to select appropriate studies. Data from these studies will be extracted and tabulated, and then reviewed for risk of bias and applicability using the QUADAS-2 tool. All evaluation will be done in duplicate. Studies with a high risk of bias and low applicability will be excluded. Meta-analysis will be performed if there are three or more studies of the same index test and food. Results: A protocol for the systematic review and meta-analyses is presented and was registered using Prospero prior to commencing the literature search. Discussion: Oral food challenges are the reference standard for diagnosis but involve considerable risks and resources. This protocol for systematic review aims to assess the accuracy of various tests to diagnose food allergy, which can be useful in both clinical and research settings.

Meta-analysis of diagnostic test accuracy in neurosurgical practice

2012 ◽  
Vol 33 (1) ◽  
pp. E5 ◽  
Author(s):  
Julie Dubourg ◽  
Moncef Berhouma ◽  
Michael Cotton ◽  
Mahmoud Messerer
Keyword(s):  
Diagnostic Test ◽  
Diagnostic Tests ◽  
Meta Analysis ◽  
Accurate Method ◽  
Diagnostic Test Accuracy ◽  
Test Accuracy ◽  
Management Options ◽  
Randomized Controlled ◽  
Controlled Treatment ◽  
Meta Analyses

Comparative effectiveness research (CER) allows evidence to be evaluated on the effectiveness, benefits, and detriments of management options, diagnostic tests, or ways to deliver health care. This process can be achieved in different ways, such as with well-designed randomized controlled trials or by meta-analyses. Several medical subspecialties are increasingly using CER, but CER remains underused by the neurosurgical community. Meta-analysis is a highly accurate method that permits results from multiple well-designed research studies to be quantitatively compared. Meta-analysis can be performed in many settings, such as the evaluation of treatment or of a diagnostic test or prognostic factor. Meta-analyses of randomized controlled treatment trials are well known, but there is a paucity of papers describing the ways to perform a meta-analysis of a diagnostic test. The aim of this paper is to improve neurosurgeons' familiarity with the meta-analysis of diagnostic test accuracy by describing and detailing each stage leading to publication.

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