Economical Regimens of Human Diploid Cell Strain Antirabies Vaccine for Post-Exposure Prophylaxis

1985 ◽  
pp. 209-217 ◽  
Author(s):  
K. G. Nicholson ◽  
M. J. Warrell ◽  
D. A. Warrell ◽  
P. Suntharasamai ◽  
C. Viravan ◽  
...  
The Lancet ◽  
1983 ◽  
Vol 322 (8345) ◽  
pp. 301-304 ◽  
Author(s):  
M.J. Warrell ◽  
Pravan Suntharasamai ◽  
Abha Sinhaseni ◽  
Rod Phanfung ◽  
J-C. Vincent-Falquet ◽  
...  

Vaccine ◽  
2011 ◽  
Vol 29 (21) ◽  
pp. 3742-3745 ◽  
Author(s):  
Ahmad Fayaz ◽  
Susan Simani ◽  
Alireza Janani ◽  
Firouzeh Farahtaj ◽  
Peyvand Biglari ◽  
...  

The Lancet ◽  
1982 ◽  
Vol 320 (8295) ◽  
pp. 436-437 ◽  
Author(s):  
Prasert Thongcharoen ◽  
Chantapong Wasi ◽  
Lersuang Chavanich

The Lancet ◽  
1985 ◽  
Vol 325 (8437) ◽  
pp. 1059-1062 ◽  
Author(s):  
M.J. Warrell ◽  
D.A. Warrell ◽  
K.G. Nicholson ◽  
Pravan Suntharasamai ◽  
Pornthep Chanthavanich ◽  
...  

1986 ◽  
Vol 96 (3) ◽  
pp. 483-489 ◽  
Author(s):  
Pravan Suntharasamai ◽  
Pornthep Chanthavanich ◽  
M. J. Warrell ◽  
Sornchai Looareesuwan ◽  
Juntra Karbwang ◽  
...  

SUMMARYNeutralizing antibody responses to conventional rabies post-exposure regimens of human diploid cell strain vaccine (HDCSV) and the new purified Vero cell rabies vaccine (PVRV) were compared in 58 healthy Thai veterinary students. The geometric mean titres (GMTs) of the group given HDCSV were slightly higher than those given PVRV, but on day 28 the peak GMTs of the two groups were statistically similar. The early antibody response to PVRV was unaffected by the addition of passive immunization, whereas the level of HDCSV response was reduced on day 14, so that there was no difference on that day between the GMTs of the two vaccine groups given HRIG. However, by day 91 the GMT of those given PVRV and HRIG was lower than in those given HDCSV alone or with HRIG. The appearance of antibody was less rapid than was observed in previous studies using multiple-site intradermal vaccination. Side effects were trivial. Our results confirm the promise of this new, potentially more economical tissue culture vaccine, but they suggest that the regimen could be improved.


Science ◽  
1977 ◽  
Vol 196 (4285) ◽  
pp. 60-63 ◽  
Author(s):  
W. Nichols ◽  
D. Murphy ◽  
V. Cristofalo ◽  
L. Toji ◽  
A. Greene ◽  
...  

1974 ◽  
Vol 146 (2) ◽  
pp. 385-390 ◽  
Author(s):  
G. A. Tomkins ◽  
E. J. Stanbridge ◽  
L. Hayflick

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