Acidic Catalysis with Zeolites

1984 ◽  
pp. 317-346 ◽  
Author(s):  
Denise Barthomeuf
Keyword(s):  
2018 ◽  
Vol 13 (11) ◽  
pp. 1934578X1801301 ◽  
Author(s):  
Alexey V. Kletskov ◽  
Vladimir I. Potkin ◽  
Irina A. Kolesnik ◽  
Sergey K. Petkevich ◽  
Anastasia V. Kvachonak ◽  
...  

Methyl 5-hydroxy-4-oxo-4 H-pyran-2-carboxylate was synthesized by esterification of methanol with comenic acid under acidic catalysis. The obtained ester was alkylated with 3-(chloromethyl)-5-phenylisoxazole and 4,5-dichloro-3-(chloromethyl)isothiazole to afford corresponding conjugates containing isoxazole and isothiazole moieties which then were transformed into water-soluble Li-salts. During the bioassays of synthesized isoxazole and isothiazole derivatives of comenic acid in mixtures with first-line antitumor drug Temobel (Temozolomid) used in brain tumors chemotherapy, a synergetic effect was observed.


2000 ◽  
Vol 63 (7) ◽  
pp. 992-994 ◽  
Author(s):  
Oxana B. Flekhter ◽  
Lidiya A. Baltina ◽  
Genrikh A. Tolstikov

ChemInform ◽  
1988 ◽  
Vol 19 (31) ◽  
Author(s):  
A. N. PUDOVIK ◽  
E. S. BATYEVA ◽  
I. S. NIZAMOV ◽  
G. U. ZAMALETDINOVA ◽  
V. A. AL'FONSOV
Keyword(s):  

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