Solid-phase synthesis of cysteine-containing peptides: Regioselective formation of disulfide bonds on the polymeric support

Peptides 1994 ◽  
1995 ◽  
pp. 285-286 ◽  
Author(s):  
S. De Rosa ◽  
L. Rusconi ◽  
R. de Castiglione ◽  
M. Galantino
Keyword(s):  
Disulfide Bonds ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Polymeric Support ◽  
Phase Synthesis

Novel and Efficient Solid-Phase Synthesis of 4,6-Disubstituted 4,5-Dihydro-3(2H)-Pyridazinones

2003 ◽  
Vol 2003 (9) ◽  
pp. 599-600
Author(s):  
Jing Tang ◽  
Xian Huang
Keyword(s):  
High Purity ◽  
Good Yield ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Malonic Ester ◽  
Polymeric Support ◽  
Subsequent Reaction ◽  
Phase Synthesis

The resin-bound 5-monosubstituted cyclic malonic ester 3 was generated and reacted with an α–bromoketone to give the corresponding 5,5-disubstituted cyclic malonic ester resin (4). Subsequent reaction with hydrazine resulted in cyclisation with concomitant cleavage from the polymeric support to release the final products, 4,6-disubstituted 4,5-dihydro-3(2 H)-pyridazinones, in good yield and high purity.

Solid-phase synthesis of peptides on the polymeric support TRILAR�

1992 ◽  
Vol 28 (2) ◽  
pp. 226-230
Author(s):  
L. K. Lubsandorzhieva ◽  
B. Khalil' ◽  
G. A. Zheltukhina ◽  
R. P. Evstigneeva
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Polymeric Support ◽  
Phase Synthesis
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