Solid phase synthesis on polymeric support with allylic anchoring groups

Peptides ◽  
1992 ◽  
pp. 502-504 ◽  
Author(s):  
H. Kunz ◽  
W. Kosch ◽  
J. März
2003 ◽  
Vol 2003 (9) ◽  
pp. 599-600
Author(s):  
Jing Tang ◽  
Xian Huang

The resin-bound 5-monosubstituted cyclic malonic ester 3 was generated and reacted with an α–bromoketone to give the corresponding 5,5-disubstituted cyclic malonic ester resin (4). Subsequent reaction with hydrazine resulted in cyclisation with concomitant cleavage from the polymeric support to release the final products, 4,6-disubstituted 4,5-dihydro-3(2 H)-pyridazinones, in good yield and high purity.


1994 ◽  
Vol 35 (25) ◽  
pp. 4437-4440 ◽  
Author(s):  
Paul Lloyd-Williams ◽  
Ahmed Merzouk ◽  
François Guibé ◽  
Fernando Albericio ◽  
Ernest Giralt

1991 ◽  
Vol 32 (33) ◽  
pp. 4207-4210 ◽  
Author(s):  
Paul Lloyd-Williams ◽  
Gemma Jou ◽  
Fernando Albericio ◽  
Ernest Giralt

1992 ◽  
Vol 28 (2) ◽  
pp. 226-230
Author(s):  
L. K. Lubsandorzhieva ◽  
B. Khalil' ◽  
G. A. Zheltukhina ◽  
R. P. Evstigneeva

Sign in / Sign up

Export Citation Format

Share Document