The Impacts of Exposure to Low Frequencies in the Human Auditory System—A Methodological Proposal

2018 ◽  
pp. 75-85
Author(s):  
Juliana Araújo Alves ◽  
Lígia Torres Silva ◽  
Paula Remoaldo
Keyword(s):  
Auditory System ◽  
Low Frequencies ◽  
Human Auditory System ◽  
System A

The human auditory system: A timeline of development

2007 ◽  
Vol 46 (9) ◽  
pp. 460-478 ◽  
Author(s):  
Jean K. Moore ◽  
Fred H. Linthicum
Keyword(s):  
Auditory System ◽  
Human Auditory System ◽  
System A

The Evolution of the Auditory System: A Tutorial

2005 ◽  
Vol 32 (Spring) ◽  
pp. 5-10 ◽  
Author(s):  
Elizabeth Hester
Keyword(s):  
Auditory System ◽  
System A

Automated complex for recording and analyzing the evoked potentials of the human auditory system

1978 ◽  
Vol 12 (2) ◽  
pp. 77-79
Author(s):  
I. V. Marchuk ◽  
A. N. Tsisarenko ◽  
�. A. Bakai
Keyword(s):  
Evoked Potentials ◽  
Auditory System ◽  
Human Auditory System

scholarly journals Deafness-in-a-dish: modeling hereditary deafness with inner ear organoids

2021 ◽  
Author(s):  
Daniel R. Romano ◽  
Eri Hashino ◽  
Rick F. Nelson
Keyword(s):  
Animal Models ◽  
Inner Ear ◽  
Auditory System ◽  
Hearing Aids ◽  
Molecular Mechanisms ◽  
Functional Disability ◽  
Experimental Studies ◽  
Hereditary Deafness ◽  
Human Auditory System ◽  
Human Inner Ear

AbstractSensorineural hearing loss (SNHL) is a major cause of functional disability in both the developed and developing world. While hearing aids and cochlear implants provide significant benefit to many with SNHL, neither targets the cellular and molecular dysfunction that ultimately underlies SNHL. The successful development of more targeted approaches, such as growth factor, stem cell, and gene therapies, will require a yet deeper understanding of the underlying molecular mechanisms of human hearing and deafness. Unfortunately, the human inner ear cannot be biopsied without causing significant, irreversible damage to the hearing or balance organ. Thus, much of our current understanding of the cellular and molecular biology of human deafness, and of the human auditory system more broadly, has been inferred from observational and experimental studies in animal models, each of which has its own advantages and limitations. In 2013, researchers described a protocol for the generation of inner ear organoids from pluripotent stem cells (PSCs), which could serve as scalable, high-fidelity alternatives to animal models. Here, we discuss the advantages and limitations of conventional models of the human auditory system, describe the generation and characteristics of PSC-derived inner ear organoids, and discuss several strategies and recent attempts to model hereditary deafness in vitro. Finally, we suggest and discuss several focus areas for the further, intensive characterization of inner ear organoids and discuss the translational applications of these novel models of the human inner ear.

scholarly journals Information Loss in the Human Auditory System

2019 ◽  
Vol 27 (3) ◽  
pp. 472-481
Author(s):  
Mohsen Zareian Jahromi ◽  
Adel Zahedi ◽  
Jesper Jensen ◽  
Jan Ostergaard
Keyword(s):  
Auditory System ◽  
Information Loss ◽  
Human Auditory System
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