Pericentric inversion of chromosome 1 in three sterile brothers

1981 ◽  
Vol 58 (2) ◽  
pp. 226-227 ◽  
Author(s):  
Alejandro Giraldo ◽  
Elizabeth Silva ◽  
In�s Mart�nez ◽  
Cristina Campos ◽  
Jes�s Guzm�n
Keyword(s):  
Pericentric Inversion ◽  
Chromosome 1

Frequency of recombinant and nonrecombinant products of pericentric inversion of chromosome 1 in sperm nuclei of carrier: By FISH technique

2003 ◽  
Vol 66 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Tahsin Yakut ◽  
Hasan Acar ◽  
�nal Egeli ◽  
Yal�in Kimya
Keyword(s):  
Pericentric Inversion ◽  
Chromosome 1 ◽  
Fish Technique ◽  
Sperm Nuclei

A Case of Chronic Lymphocytic Leukemia with a Constitutional Pericentric Inversion of Chromosome 1

2000 ◽  
Vol 118 (1) ◽  
pp. 62-64 ◽  
Author(s):  
Şükrü Palanduz ◽  
Kivanç Çefle ◽  
Melih Aktan ◽  
Gülçin Tutkan ◽  
Şükrü Öztürk ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Pericentric Inversion ◽  
Lymphocytic Leukemia ◽  
Chromosome 1

Familial pericentric inversion of chromosome 1 with a note on reproductive risks

1978 ◽  
Vol 45 (2) ◽  
pp. 123-125 ◽  
Author(s):  
Patricia N. Howard-Peebles
Keyword(s):  
Pericentric Inversion ◽  
Chromosome 1

Synapsis and synaptic adjustment in an infertile human male heterozygous for a pericentric inversion in chromosome 1

1986 ◽  
Vol 72 (2) ◽  
pp. 148-152 ◽  
Author(s):  
O. Gabriel-Robez ◽  
C. Ratomponirina ◽  
Y. Rumpler ◽  
B. Le Marec ◽  
J. M. Luciani ◽  
...  
Keyword(s):  
Pericentric Inversion ◽  
Chromosome 1 ◽  
Human Male

scholarly journals Familial pericentric inversion of chromosome 1 (p34q23) and male infertility with stage specific spermatogenic arrest.

1994 ◽  
Vol 31 (7) ◽  
pp. 573-575 ◽  
Author(s):  
D Meschede ◽  
U G Froster ◽  
M Bergmann ◽  
E Nieschlag
Keyword(s):  
Male Infertility ◽  
Pericentric Inversion ◽  
Chromosome 1

scholarly journals Pericentric inversion in human chromosome 1 and the risk for male sterility.

1987 ◽  
Vol 24 (6) ◽  
pp. 325-334 ◽  
Author(s):  
A C Chandley ◽  
S McBeath ◽  
R M Speed ◽  
L Yorston ◽  
T B Hargreave
Keyword(s):  
Human Chromosome ◽  
Male Sterility ◽  
Pericentric Inversion ◽  
Chromosome 1 ◽  
Human Chromosome 1

scholarly journals Pericentric inversion in chromosome 1 and male infertility

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 343-348
Author(s):  
Ranwei Li ◽  
Haitao Fan ◽  
Qiushuang Zhang ◽  
Xiao Yang ◽  
Peng Zhan ◽  
...  
Keyword(s):  
Genetic Counseling ◽  
Male Infertility ◽  
Pericentric Inversion ◽  
In Utero ◽  
The Other ◽  
Chromosome 1 ◽  
Spontaneous Abortions ◽  
Familial Transmission ◽  
Normal Fertility ◽  
Breakpoint Position

AbstractPericentric inversion in chromosome 1 was thought to cause male infertility through spermatogenic impairment, regardless of the breakpoint position. However, carriers of pericentric inversion in chromosome 1 have been reported with normal fertility and familial transmission. Here, we report two cases of pericentric inversion in chromosome 1. One case was detected in utero via amniocentesis, and the other case was detected after the wife of the carrier experienced two spontaneous abortions within 5 years of marriage. Here, the effect of the breakpoint position of the inversion in chromosome 1 on male infertility is examined and compared with the published cases. The association between the breakpoint of pericentric inversion in chromosome 1 and spermatogenesis is also discussed. Overall, the results suggest that the breakpoint position deserves attention from physicians in genetic counseling as inversion carriers can produce offspring.

Characterization of the human lineage-specific pericentric inversion that distinguishes human chromosome 1 from the homologous chromosomes of the great apes

2006 ◽  
Vol 120 (1) ◽  
pp. 126-138 ◽  
Author(s):  
Justyna M. Szamalek ◽  
Violaine Goidts ◽  
David N. Cooper ◽  
Horst Hameister ◽  
Hildegard Kehrer-Sawatzki
Keyword(s):  
Human Chromosome ◽  
Pericentric Inversion ◽  
Great Apes ◽  
Chromosome 1 ◽  
Human Lineage ◽  
Homologous Chromosomes ◽  
Human Chromosome 1

scholarly journals Pericentric inversion of chromosome 1 in an azoospermic man

1982 ◽  
Vol 19 (4) ◽  
pp. 303-305 ◽  
Author(s):  
A. Toth ◽  
M. Gaal ◽  
G. Sara ◽  
J. Laszlo
Keyword(s):  
Pericentric Inversion ◽  
Chromosome 1

scholarly journals Pericentric Inversion of Chromosome 1 in a Child with Low Height: Diagnostic Dilemmas

2018 ◽  
Vol 3 (5) ◽  
Keyword(s):  
Pericentric Inversion ◽  
Congenital Malformations ◽  
De Novo ◽  
Chromosomal Abnormalities ◽  
Failure To Thrive ◽  
Chromosome 1 ◽  
De Novo Mutation ◽  
Cytogenetic Testing ◽  
The Individual ◽  
Do So

The inversions are one of the most common chromosomal abnormalities. They occur when two breaks occur in a chromosome; the segment as well originated is reversed and becomes the reintegration on the same chromosome. Generally, an inversion does not cause an abnormal phenotype in the carrier, but it can do so in their offspring. Which sometimes can be associated with cases of mental retardation, congenital malformations or infertility. It is critical to determine if the inversion has a family origin, where there usually is no risks for the individual, or if it is a de novo mutation, the risk is somewhat higher, possibly due to the interruption of a key sequence of the gene. The pericentric inversion of chromosome 1 is one of the structural chromosomal variations that are not common, and it has been observed in general population and patients with abnormal phenotypes and disease. We report the case of a child that came to the office for presenting a failure to thrive every year; the cytogenetic testing reported an inversion of chromosome 1 without maternal origin nor paternal. In this case, there is no evidence that low height has relation with the abnormal chromosome.

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