Effects of indomethacin on renal hemodynamics and on water and sodium excretion by the isolated dog kidney

1975 ◽  
Vol 357 (3-4) ◽  
pp. 243-252 ◽  
Author(s):  
J. L. Vanherweghem ◽  
J. Ducobu ◽  
A. D'Hollander
Keyword(s):  
Sodium Excretion ◽  
Renal Hemodynamics ◽  
Dog Kidney ◽  
Water And Sodium Excretion ◽  
Isolated Dog Kidney

Effects of hypercalcemia on water and sodium excretion by the isolated dog kidney

1976 ◽  
Vol 363 (1) ◽  
pp. 75-80 ◽  
Author(s):  
J. -L. Vanherweghem ◽  
J. Ducobu ◽  
A. D'Hollander ◽  
C. Toussaint
Keyword(s):  
Sodium Excretion ◽  
Dog Kidney ◽  
Water And Sodium Excretion ◽  
Isolated Dog Kidney

scholarly journals Quantitative influence of non-hormonal blood factors on the control of sodium excretion by the isolated dog kidney

1972 ◽  
Vol 1 (1) ◽  
pp. 27-37 ◽  
Author(s):  
A. Nizet ◽  
A. Baerten ◽  
A. Dujardin ◽  
H. Thoumsin ◽  
J. Thoumsin-Moons
Keyword(s):  
Sodium Excretion ◽  
Dog Kidney ◽  
Isolated Dog Kidney ◽  
Quantitative Influence ◽  
Blood Factors

Prostaglandins E2 and F2αand Urinary Sodium Excretion in Isolated Dog Kidney

1979 ◽  
Vol 2 (2) ◽  
pp. 65-78 ◽  
Author(s):  
Jean-Louis Vanherweghem ◽  
Patrick Guerisse ◽  
Jean Ducobu ◽  
Alain d’Hollander ◽  
Etienne Kaivez
Keyword(s):  
Sodium Excretion ◽  
Urinary Sodium Excretion ◽  
Urinary Sodium ◽  
Dog Kidney ◽  
Isolated Dog Kidney ◽  
Prostaglandins E

Effects of hypoproteinemia on renal hemodynamics, arterial pressure, and fluid volume

1987 ◽  
Vol 252 (1) ◽  
pp. F91-F98
Author(s):  
R. D. Manning
Keyword(s):  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Sodium Excretion ◽  
Sodium Intake ◽  
Renal Plasma Flow ◽  
Urinary Sodium Excretion ◽  
Renal Hemodynamics ◽  
Fluid Volume ◽  
Urinary Sodium ◽  
Plasma Aldosterone Concentration

The effects of long-term hypoproteinemia on renal hemodynamics, arterial pressure, and fluid volume were studied in eight conscious dogs over a 34-day period. Plasma protein concentration (PPC) was decreased by daily plasmapheresis, and the effects of decreasing and increasing sodium intake were measured. By the 12th day of plasmapheresis, during which sodium intake was 30 meq/day, PPC had decreased to 2.5 g/dl from a control value of 7.2 g/dl, mean arterial pressure had decreased to 78% of control, glomerular filtration rate (GFR) was 75.2% of control, and urinary sodium excretion was decreased. By day 18 of plasmapheresis, estimated renal plasma flow (ERPF) was decreased to 60% of control due to the decreased arterial pressure and an increase in renal vascular resistance. Also, plasma renin activity and plasma aldosterone concentration were both increased, and the relationship between mean arterial pressure and urinary sodium excretion was distinctly shifted to the left along the arterial pressure axis. In contradistinction to acute experiments, chronic hypoproteinemia results in decreases in GFR, ERPF, and urinary sodium excretion and has marked effects on both fluid volume and arterial pressure regulation.

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